Written from the studies on PubMed, searched on 11 Nov 2026. Every number below comes from a study listed under Sources.
The claim
Posts online say that stem cell treatment helps with atrial fibrillation.
Where research stands
We found 45 published papers on stem cell treatment and atrial fibrillation. They were published between 2009 and 2026. None of them is a study in people. 5 were studies in animals, and 14 were only in cells in the lab. 5 papers are reviews that sum up other studies.
- 0In people
- 5In animals
- 14Only in the lab
What the studies found
We have not summed up these studies in words yet. The most important papers are listed under Sources.
Verdict
Stem cell treatment has been studied for atrial fibrillation in animals, not yet in people.
Unproven means: it was only tested in animals or cells, or there is too little or mixed data from people. How we rate claims
What this means for you: Results in animals or in cells often do not hold in people. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.
Sources
- Atrial fibrillation post hematopoietic stem cell transplant: incidence, risk factors, and management challenges.2026 · Front Cardiovasc Med · Review
- Human-induced pluripotent stem cell-atrial-specific cardiomyocytes and atrial fibrillation.2022 · World J Clin Cases · Review
- Bioengineering approaches to mature induced pluripotent stem cell-derived atrial cardiomyocytes to model atrial fibrillation.2021 · Exp Biol Med (Maywood) · Review
- Personalizing therapy for atrial fibrillation: the role of stem cell and in silico disease models.2018 · Cardiovasc Res · Review
- Atrial Fibrillation in Hematologic Malignancies, Especially After Autologous Hematopoietic Stem Cell Transplantation: Review of Risk Factors, Current Management, and Future Directions.2016 · Clin Lymphoma Myeloma Leuk · Review
- Adipose stem cell-derived exosomes circular RNA circFryl attenuate atrial fibrosis and cardiomyocyte apoptosis in atrial fibrillation.2025 · Iran J Basic Med Sci · In animals
- Development of a robust induced pluripotent stem cell atrial cardiomyocyte differentiation protocol to model atrial arrhythmia.2023 · Stem Cell Res Ther · In animals
- microRNA-148a in Exosomes Derived from Bone Marrow Mesenchymal Stem Cells Alleviates Cardiomyocyte Apoptosis in Atrial Fibrillation by Inhibiting SMOC2.2022 · Mol Biotechnol · In animals
- Exosomes from Bone Marrow Mesenchymal Stem Cells with Overexpressed Nrf2 Inhibit Cardiac Fibrosis in Rats with Atrial Fibrillation.2022 · Cardiovasc Ther · In animals
- LncRNA XIST shuttled by adipose tissue-derived mesenchymal stem cell-derived extracellular vesicles suppresses myocardial pyroptosis in atrial fibrillation by disrupting miR-214-3p-mediated Arl2 inhibition.2021 · Lab Invest · In animals
- Arrhythmic events and genetic variants as drivers for Takotsubo Syndrome: a patient-specific atrial stem-cell model.2026 · Signal Transduct Target Ther · In the lab
- Optogenetic tachypacing facilitates burst-induced arrhythmia in stem cell-derived human atrial engineered heart tissue.2026 · Europace · In the lab
- Human induced pluripotent stem cell-derived atrial cardiomyocytes recapitulate contribution of the slowly activating delayed rectifier currents IKs to repolarization in the human atrium.2024 · Europace · In the lab
- Generation of an induced pluripotent stem cell line from patient with atrial fibrillation with KCNQ1 p.Ser209Pro mutation.2024 · Stem Cell Res · In the lab
- Atrial Fibrillation After Stem Cell Transplantation: Sentinel of Systemic Vulnerability.2026 · JACC CardioOncol · Other paper
- Atrial Fibrillation Following Autologous Stem Cell Transplantation in Multiple Myeloma: Incidence, Predictors, and Prognostic Impact.2026 · JACC CardioOncol · Other paper
- Atrial fibrillation or flutter in patients undergoing stem cell transplantation, in-hospital and post-discharge outcomes in a large nationwide sample across the United States.2025 · Cardiooncology · Other paper
- Comparison of atrial fibrillation prevalence and in-hospital cardiovascular outcomes between patients undergoing allogeneic versus autologous hematopoietic stem cell transplantation: insights from the national inpatient sample.2024 · Sci Rep · Other paper
