Written based on 10 research studies on PubMed, searched on 14 Nov 2026.
The claim
Posts online say that stem cell treatment helps with trigeminal neuralgia.
Where research stands
We found 10 published papers on stem cell treatment and trigeminal neuralgia. They were published between 2011 and 2026. None of them is a study in people. 5 were studies in animals, and none was only in cells in the lab. 1 paper is a review that sums up other studies. 1 new study in people is running or will start soon, say the trial registers.
- 0In people
- 5In animals
- 0Only in the lab
What the studies found
We have not summed up these studies in words yet. The most important papers are listed under Sources.
Verdict
Stem cell treatment has been studied for trigeminal neuralgia in animals, not yet in people.
Unproven means: it was only tested in animals or cells, or there is too little or mixed data from people. How we rate claims
What this means for you: Results in animals or in cells often do not hold in people. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.
Sources
- The use of cellular therapies for trigeminal neuralgia: a systematic review of behavioral and molecular outcomes.2026 · Neurosurg Rev · Review
- Different mechanisms guide the antinociceptive effect of bone marrow-mononuclear cells and bone marrow-mesenchymal stem/stromal cells in trigeminal neuralgia.2024 · Life Sci · In animals
- Stem cells from human exfoliated deciduous teeth attenuate trigeminal neuralgia in rats by inhibiting endoplasmic reticulum stress.2022 · Korean J Pain · In animals
- Repair Effects of Bone Marrow Mesenchymal Stem Cells on Demyelination of Trigeminal Ganglion in Rats with Trigeminal Neuralgia.2022 · J Pain Res · In animals
- Stem cells from human exfoliated deciduous teeth relieve pain via downregulation of c-Jun in a rat model of trigeminal neuralgia.2022 · J Oral Rehabil · In animals
- Stem Cells from Human Exfoliated Deciduous Teeth Attenuate Trigeminal Neuralgia in Rats.2021 · Stem Cells Int · In animals
- CT-guided Foramen Ovale Injection of Mesenchymal Stem Cells: First Human Case Report of Trigeminal Neuralgia Relief.2025 · Curr Stem Cell Res Ther · Other paper
- Pluripotent stem cells-derived Schwann cells: an innovative strategy for trigeminal neuralgia?2024 · Int J Surg · Other paper
- Trigeminal neuralgia: a new therapy?2013 · Med Hypotheses · Other paper
- Extramedullary relapse presenting as trigeminal neuralgia and diplopia after allogeneic hematopoietic stem cell transplantation.2011 · Intern Med · Other paper
