University of Cambridge
Cambridge, United Kingdom
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ANCA-associated vasculitis
What is new in ANCA-associated vasculitis research, which clinical trials are open, and who works on it. From public registries and PubMed, with the source and date of every fact.
Cure status
- AvacopanPhase 3 · NCT07373262 · NCT07556484 · NCT06321601 · NCT07176546
- AzathioprinePhase 3 · NCT07168161 · NCT07138898
- BDB-001 injectionPhase 3 · NCT07168161
- BenralizumabPhase 3 · NCT04157348
- CyclophosphamidePhase 3 · NCT07490275 · NCT06375993 · NCT07168161 · NCT06733935 · NCT06983821 · NCT06152172 · NCT06308978
- Maintenance (or initiation) of immunosuppressive treatment: Imurel®, Mabthera®,Cellcept®, Cortancyl®Phase 3 · NCT03323476
- MepolizumabPhase 3 · NCT04157348
- Pioglitazone (ACTOS®)Phase 3 · NCT05946564
- PrednisonePhase 3 · NCT07168161 · NCT06983821
- Prednisone 5mg/day extended of 12 additional monthsPhase 3 · NCT03290456
- RituximabPhase 3 · NCT07168161 · NCT06047171 · NCT06388941 · NCT07138898 · NCT04871191
- Rituximab (R)Phase 3 · NCT06983821
- TocilizumabPhase 3 · NCT07138898 · NCT04871191
- TofacitinibPhase 3 · NCT07138898 · NCT04871191
- AbataceptPhase 2 · NCT07138898
- AdalimumabPhase 2 · NCT07138898
- ALE.F02Phase 2 · NCT06047171
- AnakinraPhase 2 · NCT07138898
- BCMA-CD19 CAR-T therapyPhase 2 · NCT06794008
- BelimumabPhase 2 · NCT07138898
- BimekizumabPhase 2 · NCT07138898
- CanakinumabPhase 2 · NCT07138898
- CertolizumabPhase 2 · NCT07138898
- CyclophosphamidPhase 2 · NCT06047171
- CyclosporinePhase 2 · NCT07138898
- EtanerceptPhase 2 · NCT07138898
- GlucoCorticoidPhase 2 · NCT06047171
- GlucocorticoidsPhase 2 · NCT07746180 · NCT06868290
- GolimumabPhase 2 · NCT07138898
- GuselkumabPhase 2 · NCT07138898
- HydroxychloroquinePhase 2 · NCT07138898
- Immunosuppressive AgentsPhase 2 · NCT06047171
- InfliximabPhase 2 · NCT07138898
- IptacopanPhase 2 · NCT06388941
- IxekizumabPhase 2 · NCT07138898
- LeflunomidePhase 2 · NCT07138898
- MethotrexatePhase 2 · NCT07138898
- MycophenolatePhase 2 · NCT07138898
- NM8074Phase 2 · NCT06226662
- ObinutuzumabPhase 2 · NCT06940661
- Obinutuzumab betaPhase 2 · NCT07746180
- Rapcabtagene autoleucelPhase 2 · NCT06868290
- RisankizumabPhase 2 · NCT07138898
- SecukinumabPhase 2 · NCT07138898
- SparsentanPhase 2 · NCT05630612
- SulfasalazinePhase 2 · NCT07138898
- TacrolimusPhase 2 · NCT07138898
- TarperprumigPhase 2 · NCT07160608
- TezepelumabPhase 2 · NCT06230354
- UpadacitinibPhase 2 · NCT07138898
- UstekinumabPhase 2 · NCT07138898
- VIS954Phase 2 · NCT07904806
- anti-CD19 CAR T cell therapyPhase 1/2 · NCT06828042
- anti-CD19 CAR-T cellsPhase 1/2 · NCT06821659
- CAR T cellPhase 1/2 · NCT06685042
- CC-97540Phase 1/2 · NCT07388277
- Descartes-08Phase 1/2 · NCT07089121
- FludarabinePhase 1/2 · NCT07490275 · NCT06375993 · NCT06733935 · NCT06152172 · NCT06308978
- FT839Phase 1/2 · NCT07800871
- KYV-101, an autologous fully-human anti-CD19 CAR T-cell immunotherapyPhase 1/2 · NCT06590545
- Lymphodepletion ChemotherapyPhase 1/2 · NCT07388277
- NKX019Phase 1/2 · NCT06733935
- PovetaciceptPhase 1/2 · NCT05732402
- Trimethoprim SulfamethoxazolePhase 1/2 · NCT03919435
- ADI-001Phase 1 · NCT06375993
- Allogeneic CD19/BCMA-targeted CAR-γδT cell injectionPhase 1 · NCT07490275
- BendamustinePhase 1 · NCT06308978
- CAR-T TherapyPhase 1 · NCT07033299
- FKC289Phase 1 · NCT06285279
- FT819Phase 1 · NCT06308978
- KYV-101Phase 1 · NCT06152172
- OL-108Phase 1 · NCT06980597
- QT-019CPhase 1 · NCT07315087
- SC291Phase 1 · NCT06294236
- UCAR T-cellPhase 1 · NCT07507201 · NCT07305116 · NCT06941129
- universal allogeneic anti-CD19/BCMA CAR T-cellsPhase 1 · NCT06978738
- YTS109 cellPhase 1 · NCT07104721 · NCT07236762 · NCT06978647 · NCT07236801 · NCT07439029 · NCT07123519
- anti-CD19-CAR-T cellsEarly phase 1 · NCT06420154
- anti-CD19/BCMA U CAR T cellsEarly phase 1 · NCT07246096
- BCT301Early phase 1 · NCT07301164
- CD19 or CD19-BCMA CAR-TEarly phase 1 · NCT06548607
- CD19-targeted iNKT Cell InjectionEarly phase 1 · NCT07389499
- MTS109Early phase 1 · NCT07526350
- RD06-04 Cell Injection InfusionEarly phase 1 · NCT06986018
- RD06-05 CAR-T Cell InjectionEarly phase 1 · NCT07596680
- RD06-05 CART Cell InjectionEarly phase 1 · NCT06775912 · NCT07203404
- V001-BCMAEarly phase 1 · NCT07339540
Closest to patients
- BDB-001 Phase III Trial in ANCA-Associated VasculitisPhase 3 trial: BDB-001 injection, Cyclophosphamide, RituximabJiang Su Province Hospital · Nanjing, China + 63 more hospitalsPhase 3Results expected 2027
- Safe Effective Therapy With Low-Dose Glucocorticoid in ANCA-Associated Vasculitis (SAFE-LOW)Phase 3 trial: Cyclophosphamide, Prednisone, Rituximab (R)St. Joseph's Hospital · Hamilton, Canada + 1 more hospitalPhase 3Results expected 2028
- A Trial to Evaluate the Efficacy of Pioglitazone to Promote Renal Tolerance in ANCA-associated Vasculitis - RENATO TrialPhase 3 trial: Pioglitazone (ACTOS®)Centre Hospitalier Universitaire D'Angers · Angers, France + 22 more hospitalsPhase 3Results expected 2028
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Latest news
Results, new trials and publications, newest first. Every item links to its source.
Results and new studies, newest first, in plain words.
Plain-language summary pending. Original title shown.
Publication
Rapidly Progressing Interstitial Fibrosis and Glomerulonephritis due to Granulomatosis With Polyangiitis Presenting With Calf Pain.
Rapidly Progressing Interstitial Fibrosis and Glomerulonephritis due to Granulomatosis With Polyangiitis Presenting With Calf Pain.
Clinical case reports
PubMed · PMID 42979246Review
Study outcomes for eosinophilic granulomatosis with polyangiitis and hypereosinophilic syndrome: towards achieving treatment goals in clinical practice.
Study outcomes for eosinophilic granulomatosis with polyangiitis and hypereosinophilic syndrome: towards achieving treatment goals in clinical practice.
Autoimmunity reviews
PubMed · PMID 42977011Case report
Granulomatosis with polyangiitis masquerading as lung cancer with meningeal metastasis: a case report and literature review.
Granulomatosis with polyangiitis masquerading as lung cancer with meningeal metastasis: a case report and literature review.
Frontiers in medicine
PubMed · PMID 42984555Publication
Pretreatment neutrophil-to-lymphocyte ratio is associated with clinical phenotypes and infection-related mortality in microscopic polyangiitis: the multicentre REVEAL cohort study.
Pretreatment neutrophil-to-lymphocyte ratio is associated with clinical phenotypes and infection-related mortality in microscopic polyangiitis: the multicentre REVEAL cohort study.
Frontiers in immunology
PubMed · PMID 42973739Review
[Eosinophilic granulomatosis with polyangiitis: a disease easily underestimated by rhinologists].
[Eosinophilic granulomatosis with polyangiitis: a disease easily underestimated by rhinologists].
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery
PubMed · PMID 42973020
Organisations that can help
Helplines, patient groups and support services for you and your family.
Select your country to see the organisations there, starting with the ones closest to you.
Umbrella organisations (they connect national groups)
EULAR PARE (EULAR network of organisations of People with Arthritis/Rheumatism in Europe)
Network of national patient organisations for people with rheumatic and musculoskeletal diseases (RMDs); EU-level advocacy, patient research partner training, Young PARE, webinars and support for national groups.
Visit site: EULAR PARE (EULAR network of organisations of People with Arthritis/Rheumatism in Europe)
EURORDIS – Rare Diseases Europe
Alliance of over 1,000 rare disease patient organisations, with a list of rare disease helplines by country.
Visit site: EURORDIS – Rare Diseases Europe
Vasculitis International
Global umbrella network for vasculitis patient advocacy groups and expert centres; directory of patient groups by country and of expert hospitals, patient summits, help to start groups where none exist.
Visit site: Vasculitis International
General support
For anyone who is ill, whatever the disease: patients' rights and legal aid, crisis lines, hospice and palliative care, care in another EU country, and patient organisations' umbrella bodies.
International
European Patients' Forum (EPF)
Umbrella of European patient organisations and national patient coalitions.
Visit site: European Patients' Forum (EPF)
International Alliance of Patients' Organizations
Global alliance of patient organisations of all diseases, promoting patient-centred healthcare.
Visit site: International Alliance of Patients' Organizations
Frontlight is not affiliated with these organisations; we list them because they help.
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Find fellow researchers
Groups with active ANCA-associated vasculitis work.
Inserm
Paris, France
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Université Paris Cité
Paris, France
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Assistance Publique – Hôpitaux de Paris
Paris, France
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Innsbruck Medical University
Innsbruck, Austria
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Johns Hopkins University
Baltimore, United States
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Mayo Clinic
Rochester, United States
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Universität Innsbruck
Innsbruck, Austria
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University of Pennsylvania
Philadelphia, United States
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Juntendo University
Tokyo, Japan
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Okayama University
Okayama, Japan
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Hôpital Cochin
Paris, France
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