Transcatheter aortic valve replacement in bicuspid versus tricuspid aortic valves among patients with mixed aortic valve disease.

What was studied

This study looked at people with mixed aortic valve disease. In this disease, the heart valve is both narrow and leaky. All 610 people had a new valve put in through a tube. The team compared people with a bicuspid valve to those with a tricuspid valve. Cases came from March 2013 to December 2024. The team checked deaths, daily function and heart scans.

What they found

Of the 610 people, 220 had a bicuspid valve. This group was younger, at 73 versus 75 years. They also had a lower surgery risk score. Fewer people with bicuspid valves died over the long term. With other factors counted, valve type did not clearly predict death. In the first year, the bicuspid group showed larger gains. Their valve opening and heart pumping grew more. Pressure and blood speed across the valve fell more. Both groups had a similar return of the heart muscle toward normal.

What it means for patients

The authors say both valve types had similar long-term results. People with bicuspid valves had larger gains in heart function. The authors think a bicuspid valve itself may not worsen the long-term outlook. They say this holds for carefully chosen people with this disease.

Why it is not certain yet

The record says this was a registry from a single center. People were not put into groups by chance. The groups differed in age and risk score at the start. Only carefully chosen people were studied. The abstract does not give details on side effects or valve problems.

Source

Transcatheter aortic valve replacement in bicuspid versus tricuspid aortic valves among patients with mixed aortic valve disease.

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