Cannabidiol and fronto-parietal EEG connectivity in autistic children.

What was studied

This study looked at brain wave links in autistic children who took cannabidiol oil. Each child took CBD oil and placebo, each for 12 weeks. The order was random. There was an 8-week break between them. Children who finished both periods were studied. Resting brain waves were recorded from a subset of 18 children.

What they found

Beta-band connectivity between right frontal and right parietal sites rose after CBD. Alpha connectivity also rose, but not after statistical correction. No significant differences were seen after placebo. Connectivity was measured across 16 electrode pairs.

What it means for patients

The authors link 12 weeks of cannabidiol to more connectivity. This was between right frontal and parietal sites. It was most clear in the beta band. They call this preliminary evidence.

Why it is not certain yet

Brain data came from 18 children, a subset of the trial. The authors say larger samples are needed to confirm the results. The clinical relevance is also not yet known. The alpha result did not hold after correction.

Source

Cannabidiol and fronto-parietal EEG connectivity in autistic children.

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