Early access
Sign in
Patient viewSwitch to researcher view

Brain metastases

Set up email alert
Where research stands todayUpdated 15 Nov 2026
Trial-stage treatments you can join–open now
in United States
Studies published in the last 12 months00 in people · 0 in animals · 0 in the lab
Support organisations2organisations
in United States1 helpline
Offer tissue or dataGive a sample or your health data to research.Approved treatmentsMedicines approved for brain metastases around the world.“Miracle cure” fact checkerSaw a cure online? Check it before you pay.

Trial-stage treatments and research studies you can join

Filters

Country
City
Distance is calculated in your browser. Your city is not sent to us.
Type
Get notified of new trialsUnited States, all cities, all phases
Your ageShows only trials that take people your age.
Phase
  1. Trial-stage treatmentPhase 2Soon in United States
    Phase 2 trial: Intracerebroventricular injection of MT027 UCAR-T Cell…
    Houston, United StatesAge 18 to 75
  2. Trial-stage treatmentTaking people
    Clinical trial: Steroid Therapy
    Baltimore, United StatesAlso Chicago, Cleveland, Durham, Kettering, Los Angeles, Milwaukee, St Louis, Winston-SalemAge 18+
  3. Trial-stage treatmentPhase 1Taking people
    Phase 1 trial: Ex-Vivo expanded autologous IL-8 receptor (CXCR2)…, CD70 IHC assay
    Gainesville, United StatesAge 18 to 80
  4. Trial-stage treatmentPhase 3Taking people
    Focused ultrasound to open the blood-brain barrier in lung cancer brain spread

    Tests focused ultrasound with standard immunotherapy in adults with lung cancer spread to the brain.

    Baltimore, United StatesAlso Durham, Fort Lauderdale, Miami, Newport Beach, Phoenix, Pittsburgh, Portland, Providence, …Age 18 to 100
  5. Trial-stage treatmentPhase 1/2Taking people
    Tests oral S241656 in adults with certain RAS or MAPK gene-mutated cancers

    Tests oral S241656 in adults with lung, bowel, pancreas or bile duct cancers.

    Aurora, United StatesAlso Boston, Cleveland, Durham, Fairfax, Gilbert, Grand Rapids, Houston, Los Angeles, …Age 18+
  6. Trial-stage treatmentPhase 1Taking people
    Early Phase 1 trial: Arginine, Whole-Brain Radiotherapy
    Atlanta, United StatesAge 18+
  7. Trial-stage treatmentPhase 1/2Taking people
    Phase 1/2 trial: radiosurgery
    Cleveland, United StatesAge 18+
  8. Trial-stage treatmentPhase 1/2Taking people
    Phase 1/2 trial: Elacestrant, Abemaciclib
    Boston, United StatesAlso Centerville, Detroit, Fullerton, Houston, Los Angeles, Nashville, Norfolk, Portland, …Age 18+
  9. Trial-stage treatmentPhase 2Taking people
    Phase 2 trial: Pembrolizumab, Lenvatinib
    Houston, United StatesAge 18+
  10. Trial-stage treatmentPhase 2Taking people
    Phase 2 trial: Stereotactic Radiosurgery
    Houston, United StatesAge 18+
  11. Trial-stage treatmentPhase 1Soon in United States
    Phase 1 trial: Trastuzumab Deruxtecan, Stereotactic Radiosurgery
    Miami, United StatesAge 18+
  12. Trial-stage treatmentPhase 1/2Taking people
    Tests radiation with abemaciclib for breast cancer that spread to the brain

    Tests targeted radiation with abemaciclib in adults with breast cancer spread to the brain.

    Columbus, United StatesAlso TampaAge 18+
  13. Trial-stage treatmentPhase 1/2Taking people
    Tests oral NEO212 in adults with certain brain tumors or brain metastases

    Tests oral NEO212 alone or with other treatments in adults with brain tumors or metastases.

    Beverly Hills, United StatesAlso Boston, Boynton Beach, Dallas, Glendale, Los Angeles, Nashville, TacomaAge 18+
  14. Trial-stage treatmentPhase 2Taking people
    Phase 2 trial: MA-WBRT (Memory Avoidance Whole Brain Radiation Therapy…, HA-WBRT (Hippocampal Avoidance Whole Brain Radiation…, Memantine
    Cleveland, United StatesAge 18+
  15. Trial-stage treatmentPhase 2Taking people
    Tests nivolumab, ipilimumab and cabozantinib for kidney cancer that has spread to the brain

    Tests nivolumab, ipilimumab and cabozantinib in adults with untreated kidney cancer brain metastases.

    Houston, United StatesAge 18+
  16. Trial-stage treatmentPhase 2Taking people
    Phase 2 trial: Staged Stereotactic Radiosurgery (SSRS), Fractionated Stereotactic Radiotherapy (FSRT)
    Charleston, United StatesAge 18+
  17. Trial-stage treatmentPhase 2Taking people
    Two Drug Combinations Compared for Melanoma That Has Spread to the Brain

    Compares two drug combinations in adults with melanoma that has spread to the brain.

    Aberdeen, United StatesAlso Alton, Ames, Anaconda, Anchorage, Ann Arbor, Antigo, Aurora, Aventura, …Age 18+
  18. Trial-stage treatmentPhase 2Taking people
    Tests AGuIX nanoparticles with radiation for brain metastases

    Tests whether AGuIX nanoparticles plus radiation help adults with brain cancer spread.

    Boston, United StatesAge 18+
  19. Trial-stage treatmentPhase 1Taking people
    Tests IAM1363 in adults with advanced cancers that have HER2 changes

    Tests IAM1363 for safety and dosing in adults with advanced HER2-altered cancers.

    Ann Arbor, United StatesAlso Aurora, Austin, Boston, Chicago, Cleveland, Dallas, Detroit, Durham, …Age 18+
  20. Trial-stage treatmentTaking people
    Clinical trial: Stereotactic Radiosurgery
    Basking Ridge, United StatesAlso Commack, Harrison, Middletown, Montvale, New York, Rockville CentreAge 18+

Support organisations

Patient organisations and helplines in United States, for you and your family.

We have no organisations for this disease listed in United States yet. General support there is below.

General support in United States

  • 988 Suicide & Crisis Lifeline

    US national 24/7 free and confidential lifeline for anyone in suicidal crisis or emotional distress, reachable by calling or texting 988 or by chat.

    988lifeline.org
  • MedlinePlus

    Free, easy-to-read health information service of the US National Library of Medicine (NIH) on diseases, conditions, drugs and wellness.

    medlineplus.gov

International organisations

Patient organisation umbrella bodies

Offer tissue or data

There are three ways to help research move faster.

Give tissue or bloodA biobank stores your sample so many research teams can use it.No open programme yet
Share your health dataA patient registry collects your health data, without your name, for research.How to join
Take part as a healthy volunteerStudies also need people without the disease, for comparison. Family and friends can help.Volunteer

“Miracle cure” fact checker

Social media spreads misinformation. Paste what you read here, and we'll tell you whether there is scientific evidence behind it.

What you paste is checked with AI (Anthropic, USA) and is not stored. Please leave out names and other personal details.

Before you pay for anything, ask three things

  1. Is there a published study in people?
  2. Can I have the full price in writing?
  3. What does my doctor say?

“Cures” others already fact-checked

See all 609