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Research summary ·

Nutritional supplements in the treatment of endometriosis-associated symptoms: a systematic review.

Machine-written explainer in our own words, checked against the source record · 12 Nov 2026.

What was studied

This review checked if supplements ease endometriosis symptoms. Women often use vitamins and antioxidants. The review covered trials of many supplements. The team looked at pain, quality of life, fertility and lesion growth. It had 24 trials with 2,019 women. Supplements were compared with placebo, no care or standard care.

What they found

Pain results varied. Some trials reported less pain with nanomicellar curcumin, selenium, Proscur and garlic. Omega-3, ordinary curcumin and resveratrol showed no clear gain. Fertility markers rose in some trials. Pregnancy rates did not rise. Nanocurcumin and selenium cut endometrioma size. Multinutrient care after surgery did not cut recurrence.

What it means for patients

The team says supplements may improve some symptom results. Effects depended on the product. The summary says supplements may support standard care, not replace it. The picture is one of mixed results.

Why it is not certain yet

The team says the data cannot back routine use alone. Results varied by product and by trial. Pain results were mixed. Data on lesion growth were limited. Findings were not pooled. More large trials are needed.

Source

Nutritional supplements in the treatment of endometriosis-associated symptoms: a systematic review.

PubMed · PMID 42900597

We restate facts from the source record in our own words. The original wording belongs to its publisher.

This page is not medical advice. Talk to your doctor about your own care.

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