Evaluating the landscape and characteristics of endometriosis research published between 1990 and 2024.

What was studied

This review mapped trials on endometriosis from 1990 to 2024. It studied 536 randomised trials. It looked at the type of care tested and the main outcome. It also looked at the country and the size. It then checked what size of effect each trial could detect.

What they found

Most trials tested drug care. 177 of them tested GnRH analogue drugs. Trials of complementary care grew over time. The US and China published the most, with 70 and 65 trials. Many trials were too small to detect anything but a large effect.

What it means for patients

The field leans on GnRH drugs, though these are seen as second-line care. Complementary care is getting more attention and needs more research. The authors say small trials may waste resources. China's share of trials is growing.

Why it is not certain yet

Only trials with an English abstract in one database were included. Effect sizes were estimated from trial sizes, not from real results. This review did not test any care itself. It cannot say which care works.

Source

Evaluating the landscape and characteristics of endometriosis research published between 1990 and 2024.

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