Frontlight ResearchEarly access
What researchers published on Haemophagocytic lymphohistiocytosis
681 papers, newest first.
Showing 140 of 681
Case reportTuberculosis-Associated Hemophagocytic Lymphohistiocytosis with Bone Marrow Involvement: Case Report and Literature Review.Journal of clinical medicine
ReviewEarly Toxicities of CAR-T Cell Therapy: Mechanisms, Prediction, and Management.International journal of molecular sciences
Case reportEarly recognition of a macrophage activation-associated hyperinflammatory state in anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis with rapidly progressive interstitial lung disease: a case report.Journal of medical case reports
Case reportMycoplasma pneumoniae-triggered hemophagocytic lymphohistiocytosis complicated by type I plastic bronchitis in a child: a case report.Frontiers in immunology
Case reportA fatal case of concurrent EBV-induced meningitis, ARDS, and HLH in an immunocompetent adult: a case report.Virology journal
Case reportThe Sound and the Fury: Immune Checkpoint Inhibitor-Associated Hemophagocytic Lymphohistiocytosis and Bilateral Sensorineural Hearing Loss - A Case Report.Current cancer drug targets
Case reportCase Report: Fulminant aggressive NK-cell leukemia with hemophagocytic lymphohistiocytosis and multiple organ dysfunction successfully bridged to allogeneic hematopoietic stem cell transplantation.Frontiers in immunology
Photo Quiz: A 3-year-old child with macrophage activation syndrome.Journal of clinical microbiology
Case reportSecondary Hemophagocytic Lymphohistiocytosis Triggered by Visceral Leishmaniasis in a Patient With Multiple Sclerosis Receiving Fingolimod Therapy: A Diagnostic Challenge.Cureus
Familial TLR8 gain-of-function presenting as HLH with response to IFN-γ blockade.Journal of human immunity
Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis in a Child With Coronary Artery Dilation and SARS-CoV-2 Positivity: Diagnostic Overlap With MIS-C. A Case Report.Clinical case reports
Commentary: Hemophagocytic lymphohistiocytosis induced by immune checkpoint inhibitors: observations and proposed clinical management.Frontiers in immunology
PreprintMyeloid IRF5 is required for TLR7-driven inflammatory hemophagocyte differentiation and Macrophage Activation Syndrome.bioRxiv : the preprint server for biology
Editorial: The expanding spectrum of hemophagocytic lymphohistiocytosis: pathogenic mechanisms and therapeutic implications.Frontiers in immunology
ReviewDiagnosis and management of haemophagocytic lymphohistiocytosis in adults: A narrative review and practical approach.Annals of the Academy of Medicine, Singapore
Case reportBrucella melitensis bacteraemia with lymphoma-like generalised lymphadenopathy and probable secondary haemophagocytic lymphohistiocytosis under biopsy constraints: a case report.Frontiers in immunology
Case reportHepatic Sarcoidosis as a Rare Cause of Secondary Hemophagocytic Lymphohistiocytosis.ACG case reports journal
Disseminated histoplasmosis mimicking autoimmune hepatitis as a trigger of secondary hemophagocytic lymphohistiocytosis in a pediatric patient.JPGN reports
Diffuse gastrointestinal hemorrhage associated with emapalumab treatment of macrophage activation syndrome: A case report.JPGN reports
Case reportUnraveling Immune Dysregulation in ZNFX1 Deficiency: From Interferonopathies to Macrophage Activation Syndrome.Journal of clinical immunology
Case reportSevere ARDS and secondary haemophagocytic lymphohistiocytosis complicating a flare of adult-onset Still's disease: a case-based review.Rheumatology international
Case reportListeria monocytogenes Sepsis With Meningitis Complicating Biologic Immunosuppression in a Patient With Haemophagocytic Lymphohistiocytosis Secondary to Adult-Onset Still's Disease: A Case Report.Cureus
Hemophagocytic Lymphohistiocytosis in a Patient With Alcohol-Associated Liver Disease: A Case Report Highlighting Diagnostic Challenges.Clinical case reports
Chronic Active Epstein-Barr Virus (EBV) Disease with Haemophagocytic Lymphohistiocytosis and Abnormal T/NK Cells.EJHaem
Case reportMetagenomic next-generation sequencing rescues a case of imported visceral leishmaniasis masquerading as hemophagocytic lymphohistiocytosis.Tropical biomedicine
Trial resultPlonmarlimab, a GM-CSF-neutralizing antibody, for macrophage activation syndrome.Journal of hematology & oncology
In plain wordsRead moreRead the paper on PubMedVisceral leishmaniasis associated with ixekizumab therapy presenting as hemophagocytic lymphohistiocytosis.Medicina clinica
Adult-onset familial hemophagocytic lymphohistiocytosis has distinct genetic architecture and outcomes: a nationwide multicenter cohort study in China.Biomarker research
Case reportEffectiveness of combined management of automated red cell exchange and therapeutic plasma exchange in a patient of sickle cell disease presenting with acute chest syndrome and hemophagocytic lymphohistiocytosis.Asian journal of transfusion science
Observational studyClinical Impact of Haemophagocytic Lymphohistiocytosis Among Patients With HIV/AIDS and Disseminated Histoplasmosis in a Hyperendemic Region of Northeastern Brazil.Mycoses
Case reportCase Report: Delayed diagnosis of adult-onset Still's disease after sepsis-like acute liver failure with macrophage activation syndrome.Frontiers in medicine
Case reportPersistent Type B Hyperlactataemia as a Diagnostic Clue to Occult Diffuse Large B-cell Lymphoma-Associated Haemophagocytic Lymphohistiocytosis.Cureus
Case reportBreaking the Storm: Hemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome as the First Manifestation of Systemic Lupus Erythematosus/Mixed Connective Tissue Disease in an Adolescent Successfully Treated With Anakinra.Cureus
ReviewEfficacy and Safety of Doxorubicin-Etoposide-Methylprednisolone (DEP)-Based Regimens in Haemophagocytic Lymphohistiocytosis: A Systematic Review and Meta-Analysis.European journal of haematology
Case reportSecondary hemophagocytic lymphohistiocytosis complicating culture-confirmed ceftriaxone-resistant Salmonella typhi infection: A rare case report.IDCases
Hemophagocytic Lymphohistiocytosis and Aplastic Crisis by Parvovirus B19 Infection in a Hereditary Spherocytosis Patient.Pediatrics international : official journal of the Japan Pediatric Society
ReviewResearch progress in ocular manifestations of hemophagocytic lymphohistiocytosis: Clinical features, mechanisms and therapeutic perspectives (Review).Biomedical reports
Case reportSecondary Hemophagocytic Lymphohistiocytosis Mimicking Sepsis in Adults: A Case Series.Reports (MDPI)
Anakinra for the Treatment of Severe Still's Disease Complicated With Macrophage Activation Syndrome.International journal of rheumatic diseases
Hairy cell leukemia associated haemophagocytic lymphohistiocytosis.Leukemia & lymphoma
Case reportCase Report: Adult EBV-associated hemophagocytic lymphohistiocytosis with presumed primary EBV infection: a report of three cases and diagnostic considerations.Frontiers in medicine
Macrophage activation syndrome is associated with high in-hospital mortality in patients with lupus.Lupus
Case reportBrucella melitensis infection complicated by secondary hemophagocytic lymphohistiocytosis, meningitis, and multiorgan damage: a case report and literature review.BMC infectious diseases
Hemophagocytic Lymphohistiocytosis: An Underrecognized Complication of Pediatric Crimean-Congo Hemorrhagic Fever.Pediatrics international : official journal of the Japan Pediatric Society
Syntaxin11 deficiency inhibits CRAC channel priming to suppress cytotoxicity and gene expression in T lymphocytes independent of membrane trafficking.eLife
Occult lymphoma in a 38-year-old woman with hemophagocytic lymphohistiocytosis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
Hemophagocytic Lymphohistiocytosis Thought to Be due to Undifferentiated Connective Tissue Disease Treated With Ruxolitinib: A Case Report.Case reports in rheumatology
ReviewIn the Midst of a Cytokine Storm-The Hemophagocytic Syndrome (Hemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome).Veterinary clinical pathology
Epstein-barr virus-associated hemophagocytic lymphohistiocytosis after antithymocyte globulin-conditioned allogeneic hematopoietic stem cell transplantation: a single-center case series.Annals of hematology
Transcriptomic evidence of an IFN-gamma-associated inflammatory state in active visceral leishmaniasis: an exploratory comparison with pediatric HLH.Frontiers in cellular and infection microbiology
H1N1-Related Hemophagocytic Lymphohistiocytosis Complicated by Severe Rhabdomyolysis in a Pediatric Patient: A First Case Report.Case reports in pediatrics
ReviewThe DRESS/HLH Overlap Syndrome: A Systematic Review of Clinical Features, Triggers, and Outcomes.Journal of clinical medicine
Kikuchi-Fujimoto disease with hemophagocytic lymphohistiocytosis in children: a seven-patient case series.Frontiers in immunology
Hyperinflammatory differentiation syndrome with hemophagocytic lymphohistiocytosis-like features following menin inhibition in acute myeloid leukemia.Haematologica
[Clinical characterization and prognosis of connective tissue disease-associated hemophago-cytic syndrome in adults].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
Case reportPostpartum macrophage activation syndrome with temporal dissociation of cytopenias in a patient with Kikuchi-Fujimoto disease and undifferentiated connective tissue disease: a case report.AME case reports
Diagnostic Value of Skin Biopsy in Fatal Histoplasmosis-Associated Hemophagocytic Lymphohistiocytosis: A Case Report.Dermatology and therapy
Time-Dependent Prognostic Value of the sCD25-to-Ferritin Ratio in Chronic Active Epstein-Barr Virus-Associated Hemophagocytic Lymphohistiocytosis.Infectious diseases and therapy
Case reportHaemophagocytic Lymphohistiocytosis Triggered by Visceral Leishmaniasis Masquerading as Epstein-Barr Virus (EBV)-Associated Haemophagocytic Lymphohistiocytosis in Rheumatoid Arthritis: A Case Report and Literature Review.Cureus
Case reportNeonatal-onset familial hemophagocytic lymphohistiocytosis type 2: a case report.Frontiers in pediatrics
ReviewEpstein-Barr virus and hepatic failure: pathogenesis, clinical manifestations, and management.Frontiers in immunology
[Salvage allogeneic hematopoietic stem cell transplantation in five patients with refractory angioimmunoblastic T-cell lymphoma complicated by hemophagocytic lymphohistiocytosis: a case series].Zhonghua nei ke za zhi
Early C-reactive protein and ferritin kinetics after tocilizumab initiation predict macrophage activation syndrome in Still disease: a single-centre retrospective cohort study.EULAR rheumatology open
Hemophagocytic Lymphohistiocytosis Criteria Overlap with Severe Malaria Features in Children.Open forum infectious diseases
Case reportFatal haemophagocytic lymphohistiocytosis and atypical haemolytic uraemic syndrome following coronavirus disease 2019 infection.BMJ case reports
Case reportCase Report: Hemophagocytic lymphohistiocytosis in an infant associated with cytomegalovirus infection and X-linked primary immunodeficiency.Frontiers in immunology
Haemophagocytic Lymphohistiocytosis Following Severe Erysipelas with EBV Reactivation.Acta dermato-venereologica
An Active Cytomegalovirus Infection and Epstein-Barr Virus Reactivation Complicated by Cytomegalovirus Meningitis and Virus-Associated Hemophagocytic Lymphohistiocytosis during Methotrexate and Upadacitinib Therapy in a Patient with Rheumatoid Arthritis.Internal medicine (Tokyo, Japan)
Case reportHaemophagocytic lymphohistiocytosis triggered by Kikuchi-Fujimoto disease: a diagnostic challenge.BMJ case reports
Case reportDifferentiating Persistent Sepsis From Pembrolizumab-Induced Secondary Hemophagocytic Lymphohistiocytosis and Concurrent Immune-Mediated Nephritis: A Diagnostic and Therapeutic Challenge.Cureus
Case reportHyperinflammatory syndromes in primary mitochondrial disease: A three-center case series and focused review.Molecular genetics and metabolism
Case reportAngioimmunoblastic T-cell lymphoma with secondary hemophagocytic lymphohistiocytosis initially misdiagnosed as classical Hodgkin lymphoma: A case report.Medicine
Interferon-γ as a predictive biomarker for macrophage activation syndrome in systemic JIA: a chinese multicenter study.Clinical rheumatology
Scrub typhus triggers hemophagocytic lymphohistiocytosis in children: metagenomic next-generation sequencing enables rapid diagnosis.Frontiers in public health
Case reportCase Report: Reconciling genomic ambiguity with clinical certainty in refractory panniculitis.Frontiers in immunology
GuidelineConsensus recommendations for the diagnosis and management of hemophagocytic lymphohistiocytosis in the Gulf Cooperation Council: a modified Delphi approach.Frontiers in immunology
In plain wordsRead moreRead the paper on PubMedFelty's syndrome complicated by macrophage activation syndrome in long-standing seropositive rheumatoid arthritis.Medicina clinica
Severe Plasmodium vivax Malaria Complicated by Secondary Hemophagocytic Lymphohistiocytosis, Disseminated Intravascular Coagulation, and Acute Pancreatitis: A Case Report.Clinical case reports
[Prognostic Value of Serum Total Bilirubin in Lymphoma-Associated Hemophagocytic Lymphohistiocytosis].Zhongguo shi yan xue ye xue za zhi
ReviewBridging Autoimmunity and Hyperinflammation: Shared Immunological Pathways Among Autoimmune/Inflammatory Syndrome Induced by Adjuvants, Systemic Lupus Erythematosus, and Macrophage Activation Syndrome.Biomedicines
Case reportRapid response to high-dose Anakinra in refractory SLE-associated Haemophagocytic Lymphohistiocytosis: a case report.Oxford medical case reports
Case reportConcurrent Catastrophic Antiphospholipid Syndrome, Hemophagocytic Lymphohistiocytosis, and Myocarditis Leading to Multi-organ Failure in a Patient With Systemic Lupus Erythematosus and Antiphospholipid Syndrome.Cureus
Case reportRefractory Graves' Disease With Propylthiouracil-Induced Hemophagocytic Lymphohistiocytosis and Multiple Drug Allergies Treated With Total Thyroidectomy: A Case Report.Cureus
Case reportCase Report: Definite DRESS following phenobarbital exposure with secondary HLH and DAT-positive hemolysis during high-dose IVIG treatment in a child.Frontiers in immunology
Case reportA case of neonatal galactosemia presenting with rare hematologic problems: factor V deficiency and hemophagocytic lymphohistiocytosis.The Turkish journal of pediatrics
Exploratory analysis of IFN-α-high and CXCL9-high cytokine distributions in systemic lupus erythematosus-associated macrophage activation syndrome.Immunological medicine
Treatment Approaches to Macrophage Activation Syndrome in Real Life and Priorities for Future Research: Results From the International METAPHOR Project.Arthritis & rheumatology (Hoboken, N.J.)
Guideline[Guidelines for the diagnosis and treatment of hemophagocytic lymphohistiocytosis (2026 edition)].Zhonghua yi xue za zhi
In plain wordsRead moreRead the paper on PubMedThe diagnostic utility of the soluble CD25-to-ferritin ratio in lymphoma-associated hemophagocytic lymphohistiocytosis.Leukemia research
Delayed Recognition of Hemophagocytic Lymphohistiocytosis in a Child With Refractory Fever: A Case From Pakistan.Clinical case reports
Hemophagocytic Lymphohistiocytosis in a Patient With Gaucher Disease Having a Homozygous STXBP3 Variant.Pediatric blood & cancer
ReviewPrecision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care.Pediatric investigation
ReviewBeyond the Storm: CXCL9 and the New Era of Precision Hemophagocytic Lymphohistiocytosis Diagnostics.Diagnostics (Basel, Switzerland)
Case reportOral manifestations and management of lymphoma-associated hemophagocytic lymphohistiocytosis.Journal of stomatology, oral and maxillofacial surgery
Case reportHaemophagocytic lymphohistiocytosis complicating typhoid fever: A case report from Senegal.IDCases
Could Mixed CAR T-Cell Products and Overlapping Patients Overestimate the Risk of HLH With Tisagenlecleucel?American journal of hematology
ReviewImmune Checkpoint Inhibitor-Associated Hemophagocytic Lymphohistiocytosis: A Systematic Review.Clinical Medicine Insights. Oncology
Allogeneic Hematopoietic Stem Cell Transplantation in Hemophagocytic Lymphohistiocytosis: Therapeutic Role and Trigger of Post-Transplant Hyperinflammation.Mediterranean journal of hematology and infectious diseases
Macrophage activation syndrome in systemic lupus erythematous and Still's disease: distinct phenotypes shaped by the underlying diseases.Rheumatology (Oxford, England)
Envenomation-Induced Hemophagocytic Lymphohistiocytosis (HLH): First Reported Adult Case Following A Spider Bite.European journal of case reports in internal medicine
Development of a machine learning-based assistive diagnostic model for Epstein‑Barr virus‑associated hemophagocytic lymphohistiocytosis in pediatric patients.Translational pediatrics
Case reportMacrophage activation syndrome in a 13-month-old child with systemic juvenile idiopathic arthritis mimicking sepsis: a diagnostic challenge and case report.Annals of medicine and surgery (2012)
Unmasking Macrophage Activation Syndrome in Vexas Syndrome: A Diagnostic Challenge.European journal of case reports in internal medicine
ReviewA systematic review of juvenile dermatomyositis complicated by macrophage activation syndrome.Current opinion in immunology
Case reportHemophagocytic Lymphohistiocytosis as the Initial Presentation of Acute HIV Infection: A Case Report.Cureus
Case reportLeflunomide-Induced Severe Cutaneous Adverse Reaction, Severe Drug-Induced Liver Injury With Hepatic Encephalopathy, and Hemophagocytic Lymphohistiocytosis: A Case Report.Cureus
Navigating the Gray Zone: Differentiating Sepsis and Secondary HLH in Adults Using T Cell Activation Markers.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion
Clinical Profile and Outcomes of Pediatric Secondary HLH: Insights from a Tertiary Care Hospital.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion
ReviewHemophagocytic lymphohistiocytosis in critically ill patients: A guide for clinicians.World journal of critical care medicine
AMETHYST: A Retrospective Cohort Study of Treatment Patterns and Outcomes in Patients With Glucocorticoid-Refractory Macrophage Activation Syndrome Complicating Still's Disease.Arthritis & rheumatology (Hoboken, N.J.)
Review[Mechanism and clinical progress of JAK inhibitors in hemophagocytic lymphohistiocytosis].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi
Hemophagocytic Lymphohistiocytosis Following Systemic Bacillus Calmette-Guérin Infection: A Rare Complication of a Common Procedure.The Israel Medical Association journal : IMAJ
Peritoneal effusion as a marker of disease severity in secondary hemophagocytic lymphohistiocytosis: Clinical and immunological insights.SAGE open medicine
Case reportTuberculosis presenting as dual immune dysregulation: Evans syndrome and haemophagocytic lymphohistiocytosis.BMJ case reports
Case reportHemophagocytic Lymphohistiocytosis Complicated With Reversible Cardiomyopathy and Severe Sinus Node Dysfunction.JACC. Case reports
Robustness of Hemophagocytic Lymphohistiocytosis Risk Estimates in CAR T-Cell Therapy.American journal of hematology
Case reportTwo Cases of Feline Hepatosplenic Cytotoxic T-Cell Lymphoma With Hemophagocytosis.Veterinary clinical pathology
Case reportWhich Factors May Contribute to a Successful Outcome in Hemophagocytic Lymphohistiocytosis: A Case Report.Cureus
A Three-Component Immune Framework Stratifies Treatment Response and Escalation in Pediatric Hemophagocytic Lymphohistiocytosis: A Prospective Single-Center Cohort Study.Pediatric blood & cancer
Spectrum of Primary Hemophagocytic Lymphohistiocytosis-Associated Gene Mutations in Chinese Patients.MedComm
Case reportNeonatal Aicardi-Goutières syndrome presenting with macrophage activation syndrome-like hyperinflammation and severe congenital glaucoma: a case report.Pediatric rheumatology online journal
ReviewDistinct Clinical and Prognostic Features of Acute and Chronic Active Epstein-Barr Virus-Associated Hemophagocytic Lymphohistiocytosis in Adults: A Scoping Review.ImmunoTargets and therapy
Case reportHemophagocytic Lymphohistiocytosis As the Initial Presentation of Occult Diffuse Large B-cell Lymphoma: A Diagnostic Challenge.Cureus
Use of Extracorporeal Membrane Oxygenation (ECMO) in Pediatric Patients With Hemophagocytic Lymphohistiocytosis: A Multicenter Sub-Analysis.ASAIO journal (American Society for Artificial Internal Organs : 1992)
Case reportToxoplasmosis-associated hemophagocytic lymphohistiocytosis during tumor-infiltrating lymphocyte therapy.ASM case reports
Ruxolitinib for rheumatic disease-associated macrophage activation syndrome in children: a retrospective cohort study.Frontiers in immunology
Case reportClinical analysis of HIV co-infection with Talaromyces marneffei complicated by hemophagocytic syndrome.Diagnostic microbiology and infectious disease
Case reportBabesiosis at ultra-low parasitemia presenting as secondary hemophagocytic lymphohistiocytosis in a patient on B cell-depleting therapy.ASM case reports
Case reportRefractory Kawasaki Disease in Infants Complicated with Giant Coronary Artery Aneurysms and Takayasu Arteritis: A Rare Case Report and Literature Review.Vascular health and risk management
Persistent Interleukin-18 Fuels Expansion of CD38+HLA-DR+CD8+ T Cells in Still Disease and Macrophage Activation Syndrome.Arthritis & rheumatology (Hoboken, N.J.)
The prognostic value of liver function abnormalities in adult secondary hemophagocytic lymphohistiocytosis.Frontiers in medicine
Comprehensive Viral Detection and Profiling of Plasma Cell-Free RNA in Patients With Suspected Hemophagocytic Lymphohistiocytosis.Journal of medical virology
Diagnostic performance of HScore for macrophage activation syndrome complicating Still's disease in adults: a multicentre case-control study.Rheumatology (Oxford, England)
Case reportSecondary Hemophagocytic lymphohistiocytosis in an immunocompetent adult: a case report distinguishing sarcoidosis from histoplasmosis.Diagnostic microbiology and infectious disease
Case reportCD56-Positive Acute Myeloid Leukemia Complicated by Hemophagocytic Lymphohistiocytosis: A case report and narrative review.Pakistan journal of medical sciences
Case reportSuccessful treatment of refractory hemophagocytic lymphohistiocytosis complicating Epstein-Barr virus-positive classic Hodgkin lymphoma with rituximab.Journal of clinical and experimental hematopathology : JCEH
ReviewPrognostic Factors Associated With Mortality in Adult Hemophagocytic Lymphohistiocytosis: A Systematic Review and Meta-Analysis.Cureus
Case report[HAVCR2-mutated subcutaneous panniculitis-like T-cell lymphoma presenting with bone marrow infiltration and rapidly fatal hemophagocytic lymphohistiocytosis].[Rinsho ketsueki] The Japanese journal of clinical hematology
Case reportDiagnosis and treatment of familial hemophagocytic lymphohistiocytosis with isolated central nervous system involvement: A case report.Annals of hematology
ReviewTreatment strategies for relapsed/refractory hemophagocytic lymphohistiocytosis in pediatric patients.Therapeutic advances in hematology