Impact of Aortic Annulus Size on Outcomes After Aortic Valve Replacement: The PARTNER 3 Trial.

What was studied

This is a later analysis of the PARTNER 3 trial. It included low-risk people with severe aortic stenosis and symptoms. They were randomly given a catheter valve or open-heart valve surgery. The catheter valve was the SAPIEN 3. The team asked if aortic annulus size changed 5-year outcomes. 925 people had scans of annulus size.

What they found

The main outcome was death, stroke, or return to hospital. Over 5 years, rates were similar for both treatments. That held for small annuli and for large annuli. Valve failure was similar in both groups. Health status was also similar. Annulus size did not change these results.

What it means for patients

The authors conclude that the catheter valve gave similar 5-year results to surgery. They say this held no matter the annulus size.

Why it is not certain yet

This was a post hoc analysis, done after the main trial. It covers low-risk people only. Splitting by annulus size leaves fewer people in each group. The abstract does not give results beyond 5 years.

Source

Impact of Aortic Annulus Size on Outcomes After Aortic Valve Replacement: The PARTNER 3 Trial.

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