First Affiliated Hospital of GuangXi Medical University
Nanning, China
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Thalassaemia
FollowWhat is new in Thalassaemia research, which clinical trials are open, and who works on it. From public registries and PubMed, with the source and date of every fact.
Cure status
- Alpha Lipoic Acid 600 MG Oral TabletsPhase 3 · NCT07157722
- CTX001Phase 3 · NCT05356195 · NCT05477563 · NCT04208529
- DanazolPhase 3 · NCT07884773
- Etavopivat APhase 3 · NCT06609226
- Etavopivat BPhase 3 · NCT06609226
- Etavopivat CPhase 3 · NCT06609226
- Iron chelating interventionPhase 3 · NCT07157722
- LuspaterceptPhase 3 · NCT04064060 · NCT05567458
- MitapivatPhase 3 · NCT07517133 · NCT04770779 · NCT07506863 · NCT04770753
- Mitapivat Matched PlaceboPhase 3 · NCT07506863
- N Acetyl cysteine 600mgPhase 3 · NCT07157722
- PrednisolonePhase 3 · NCT07884773
- ThalidomidePhase 3 · NCT06490627 · NCT06490601 · NCT07884773
- ACE-536Phase 2 · NCT04143724
- AlemtuzumabPhase 2 · NCT02105766 · NCT05357482 · NCT03653338 · NCT00061568 · NCT00977691 · NCT07599176
- alpha beta depletionPhase 2 · NCT04099966
- BortezomibPhase 2 · NCT05736419
- CyclophosphamidePhase 2 · NCT02105766 · NCT05736419 · NCT00977691
- DefibrotidePhase 2 · NCT02675959
- DexamethasonePhase 2 · NCT05736419
- FilgrastimPhase 2 · NCT02105766
- FludarabinePhase 2 · NCT03653338 · NCT05736419
- FT007Phase 2 · NCT07680803
- HGI-001 InjectionPhase 2 · NCT07721480
- Mycophenolate MofetilPhase 2 · NCT05736419
- PentostatinPhase 2 · NCT02105766
- Rabbit ATGPhase 2 · NCT05736419
- RadiotherapyPhase 2 · NCT02105766
- REGN7999Phase 2 · NCT06421636
- RituximabPhase 2 · NCT03653338 · NCT05736419
- SirolimusPhase 2 · NCT02105766 · NCT05357482 · NCT00061568 · NCT00977691
- SP-420Phase 2 · NCT05693909
- TacrolimusPhase 2 · NCT05736419
- thalidomide and hydroxyureaPhase 2 · NCT06490601
- AbataceptPhase 1/2 · NCT07599176
- ALS20Phase 1/2 · NCT06364774
- Benserazide Only ProductPhase 1/2 · NCT04432623
- briquilimabPhase 1/2 · NCT05357482
- BRL-101Phase 1/2 · NCT05577312
- CD3/CD19 depleted leukocytesPhase 1/2 · NCT03653338
- CD34 Stem Cell Selection TherapyPhase 1/2 · NCT01966367
- CD45RA depleted leukocytesPhase 1/2 · NCT03653338
- CliniMACS CD34 ReagentPhase 1/2 · NCT04008368
- EDIT-301Phase 1/2 · NCT05444894
- Filgrastim (G-CSF)Phase 1/2 · NCT05357482
- HydroxyureaPhase 1/2 · NCT05357482 · NCT03653338
- KL003 Cell Injection Drug ProductPhase 1/2 · NCT06280378
- Low Dose IrradiationPhase 1/2 · NCT00977691
- PBSC TransplantPhase 1/2 · NCT00977691
- Peripheral blood hematopoietic progenitor cell (PBPC) transplantPhase 1/2 · NCT00061568
- Peripheral blood hematopoietic progenitor cell ApheresisPhase 1/2 · NCT00061568
- PlerixaforPhase 1/2 · NCT05357482
- TBIPhase 1/2 · NCT05357482
- ThiotepaPhase 1/2 · NCT03653338
- Total Body IrradiationPhase 1/2 · NCT07599176
- Vebeglogene autotemcelPhase 1/2 · NCT06308159
- 9MW3011Phase 1 · NCT06772766
- 9MW3011 placeboPhase 1 · NCT06772766
- autologous bone marrow derived CD34+ HSPCs electroporated with BCL11A enhancer targeting Cas9 ribonucleoproteinPhase 1 · NCT06647979
- BD211Phase 1 · NCT06465550
- panobinostatPhase 1 · NCT01245179
- Sequencing Assay for Variant rs114518452Phase 1 · NCT06647979
- CS-101Early phase 1 · NCT06328764
- GMCN-508B (LentiRed)Early phase 1 · NCT05762510
Closest to patients
- A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Non-Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-NTDT)A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Non-Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-NTDT)Hospital Universitario La Paz · Madrid, Spain + 67 more hospitalsPhase 3Primary completion 2023
- A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT)A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT)Universitair Medisch Centrum Utrecht · Utrecht, Netherlands + 71 more hospitalsPhase 3Primary completion 2024
- Evaluating the Effect of N-Acetyl Cysteine and Alpha Lipoic Acid in Patients With Beta ThalassemiaEvaluating the Effect of N-Acetyl Cysteine and Alpha Lipoic Acid in Patients With Beta ThalassemiaFaculty of Pharmacy, Tanta University · Tanta, EgyptPhase 3Primary completion 2025
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Latest news
Results, new trials and publications, newest first. Every item links to its source.
Results and new studies, newest first, in plain words.
Plain-language summary pending. Original title shown.
Publication
Colorimetric detection of SEA-type α-thalassemia via hairpin-mediated EXPAR and G-quadruplex self-assembly in clinical patients.
Colorimetric detection of SEA-type α-thalassemia via hairpin-mediated EXPAR and G-quadruplex self-assembly in clinical patients.
Chemical communications (Cambridge, England)
PubMed · PMID 42979724Publication
Probable Deferasirox-Associated Acute-on-Chronic Liver Failure in Non-Transfusion-Dependent β-Thalassemia with Iron-Related Cirrhosis: A Case Report.
Probable Deferasirox-Associated Acute-on-Chronic Liver Failure in Non-Transfusion-Dependent β-Thalassemia with Iron-Related Cirrhosis: A Case Report.
Hemoglobin
PubMed · PMID 42982425Publication
Perspectives of healthcare workers on sickle cell disease in tribal India: insights for strengthening the National Sickle Cell Anaemia Elimination Mission of India.
Perspectives of healthcare workers on sickle cell disease in tribal India: insights for strengthening the National Sickle Cell Anaemia Elimination Mission of India.
Journal of community genetics
PubMed · PMID 42980947
Organisations that can help
Helplines, patient groups and support services for you and your family.
International & European
European Patients' Forum (EPF)
Umbrella of European patient organisations and national patient coalitions.
Visit site: European Patients' Forum (EPF)EURORDIS – Rare Diseases Europe
Alliance of over 1,000 rare disease patient organisations, with a list of rare disease helplines by country.
Visit site: EURORDIS – Rare Diseases EuropeInternational Alliance of Patients' Organizations
Global alliance of patient organisations of all diseases, promoting patient-centred healthcare.
Visit site: International Alliance of Patients' OrganizationsThalassaemia International Federation
Covers thalassaemia, sickle cell disease and other rare anaemias: patient education, TIFLIX video library; set up and runs the secretariat of the International Active SCD Group (IASG), an informal network of patient-led sickle cell organisations.
Visit site: Thalassaemia International Federation
Frontlight is not affiliated with these organisations; we list them because they help.
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Find fellow researchers
Groups with active Thalassaemia work.
Mahidol University
Bangkok, Thailand
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National and Kapodistrian University of Athens
Athens, Greece
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Chiang Mai University
Chiang Mai, Thailand
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Guangxi Medical University
Nanning, China
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Southern Medical University
Guangzhou, China
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Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, Italy
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St. Jude Children's Research Hospital
Memphis, United States
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Harvard University
Cambridge, United States
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Children's Hospital of Philadelphia
Philadelphia, United States
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University of California, San Francisco
San Francisco, United States
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Weill Cornell Medicine
New York, United States
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