Clinical trials

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58 trials

NCT07884773
Recruiting
Combination Therapy With Danazol, Prednisolone, and Thalidomide for Thalidomide-Refractory Transfusion-Dependent β-Thalassemia
Phase 3 · Pakistan · 1 site
Registry update: 21 Oct 2026
NCT07506863
Recruiting
A Study to Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT)
Phase 3 · Greece, Italy, United States · 8 sites
Registry update: 29 Oct 2026
NCT07517133
Recruiting
A Study to Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Participants With α- or β-Non-Transfusion-Dependent Thalassemia
Phase 3 · Greece, Italy, United States · 7 sites
Registry update: 28 Oct 2026
NCT07599176
Recruiting
Partial Stem Cell Transplant for Sickle Cell Disease From Matched Donors
Phase 1/2 · United States · 1 site
Registry update: 13 Oct 2026
NCT07680803
Recruiting
Gene-Modified Stem Cell Therapy for Subjects With Transfusion-dependent Beta-thalassemia
Phase 2 · Italy · 2 sites
Registry update: 27 Jul 2026
NCT07215975
Recruiting
A Real-World Study to Evaluate Luspatercept in Adults With Transfusion-Dependent Beta-Thalassemia in the Middle East
Not applicable · United Arab Emirates, Kuwait, Oman, Saudi Arabia · 13 sites
Registry update: 19 Aug 2026
NCT07673302
Recruiting
Safety and Efficacy of Hemoglobin F Inducers in Patients With Beta Thalassemia
Not applicable · Pakistan · 1 site
Registry update: 6 Aug 2026
NCT07338344
Recruiting
Evaluating the Clinical Efficacy and Safety of Luspatercept Combined With Thalidomide in the Treatment of β-TDT Patients
Phase 2 · China · 8 sites
Registry update: 13 Jan 2026
NCT07725263
Recruiting
Low-Dose Liposomal Amphotericin B for Invasive Fungal Infection Prophylaxis in Neutropenic Children
Not applicable · China · 1 site
Registry update: 24 Jul 2026
NCT06647979
Recruiting
Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-Hemoglobinopathies
Phase 1 · United States · 1 site
Registry update: 3 Feb 2026
NCT07207577
Recruiting
Evaluation of Physiological and Psychological Factors Involved in Exercise Intolerance in Patients With β-TTD
Not applicable · France · 1 site
Registry update: 7 Oct 2026
NCT06743477
Recruiting
A Clinical Study of Ultra-transplantation for the Treatment of Major Thalassemia Scheme
Not applicable · China · 1 site
Registry update: 2 Sept 2025
NCT07112703
Recruiting
Effect of Incentive Respiratory Training on Pulmonary Functions and Functional Capacity in Children With B-thalassemia Major
Not applicable · Egypt · 1 site
Registry update: 8 Aug 2025
NCT06609226
Recruiting
A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia
Phase 3 · Canada, Germany, Egypt, Spain, France, United Kingdom, Ghana, Greece, India, Italy, Kenya, Lebanon, Nigeria, Oman, Saudi Arabia, United States · 101 sites
Registry update: 18 Sept 2026
Conflicting statuses (not updated in the registry for 1 month)
NCT06772766
Recruiting
A Multiple Ascending Dose Study of 9MW3011 in Patients With Non-transfusion-dependent β-thalassemia
Phase 1 · China · 2 sites
Registry update: 14 Jan 2025
NCT07177300
Recruiting
Effectiveness of Nontraditional Hydroxyurea Algorithms: Novel and Clinical Evaluations (ENHANCE)
Phase 4 · United States · 1 site
Registry update: 16 Sept 2025
NCT06298630
Recruiting
Long-term Follow-up Study of BRL-101 for TDT
Not applicable · China · 7 sites
Registry update: 21 Jul 2026
NCT05414045
Recruiting
Autologous Testicular Tissue Transplantation
Not applicable · Belgium · 1 site
Registry update: 23 Apr 2026
NCT06734520
Recruiting
Clinical Study of Super Transplantation in the Treatment of Severe β-thalassemia
Not applicable · China · 1 site
Registry update: 16 Dec 2024
Conflicting statuses (not updated in the registry for 22 months)
NCT06657391
Recruiting
Evaluation of Recombinant Humanized Anti-CD25 Monoclonal Antibody for Preventing Graft-versus-host Disease After Haploidentical/matched Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients with Transfusion-dependent Thalassemia
Phase 2 · China · 5 sites
Registry update: 28 Oct 2024

Ordered by registry start date. Freshness and sponsorship never change the order.