Lupus (SLE): trials for referral
414 open trials in the registries we read. Each row links to its registry record.
Registry data only. Frontlight does not judge whether a patient can take part: the trial team decides.
Where the open trials are
Type a city to sort by distance. The distance is worked out in your browser; the city is not sent anywhere.
400 trials shown · Showing the 400 most recently updated of 414 open trials.
Phase 1/22 sites
RecruitingUnited States
NCT06434363
Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders
M.D. Anderson Cancer Center
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govPhase 3273 sites
RecruitingArgentina, Australia, Bulgaria, Brazil, Switzerland, China
NCT07438496
A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus
Janssen Research & Development, LLC
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govNo phase2 sites
RecruitingPeru, United States
NCT06948110
Deciphering the Genetic Architecture of Autoimmune Diseases
National Human Genome Research Institute (NHGRI)
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govPhase 242 sites
RecruitingBrazil, Canada, Spain, France, United Kingdom, Italy
NCT05039619
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants
Hoffmann-La Roche
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited Kingdom
NCT07913919
Effect of Anifrolumab on Arterial Inflammation in Systemic Lupus Erythematosus Study
University of Cambridge
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
Not yet recruitingChina
NCT07901764
MYTP01 for Immune-Mediated Diseases
Zhejiang Provincial People's Hospital
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govNo phase70 sites
RecruitingArgentina, Brazil, Canada, Germany, Spain, France
NCT07175285
A Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 Immunosuppressants
Bristol-Myers Squibb
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govPhase 118 sites
RecruitingCanada, United States
NCT07085104
A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease
Allogene Therapeutics
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govPhase 3253 sites
RecruitingUnited Arab Emirates, Argentina, Belgium, Canada, Chile, China
NCT06617325
A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus
UCB Biopharma SRL
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govPhase 124 sites
RecruitingAustralia, Belgium, China, Colombia, Spain, Georgia
NCT07363590
A Clinical Study of MK-1045 in People With Lupus or Rheumatoid Arthritis (MK-1045-004)
Merck Sharp & Dohme LLC
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govPhase 216 sites
RecruitingBrazil, United Kingdom, Greece, United States, Vietnam
NCT07053800
Obe-cel in Severe, Refractory Systemic Lupus Erythematosus (SLE) With Active Lupus Nephritis (LN)
Autolus Limited
Registry updated 30 Oct 2026
Registry record: ClinicalTrials.govPhase 1/23 sites
Not yet recruitingFrance
2026-526117-28-00
Phase 1/2 study to evaluate the safety, pharmacokinetics, and preliminary efficacy of SAR447998 in adults with refractory Systemic Lupus Erythematosus or Rheumatoid Arthritis
Sanofi-Aventis Recherche & Developpement
Registry updated 30 Oct 2026
Registry record: EU CTISPhase 10 sites
Not yet recruiting
NCT07906145
A Phase 1 Study of QLS2416 Injection in Participants With Autoimmune Diseases
Shanghai Qilu Pharmaceutical Research and Development Center LTD
Registry updated 30 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT00001372
Study of Systemic Lupus Erythematosus
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingPakistan
NCT07902622
Pakistan Arthritis and Connective Tissue Disease Network - Systemic Lupus Erythematosus
Foundation University Islamabad
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govPhase 216 sites
Not yet recruitingBulgaria, Spain, Hungary, Poland
2026-527200-24-00
A Trial of LAD603 in Patients with Systemic Lupus Erythematosus
Almirall S.A.
Registry updated 29 Oct 2026
Registry record: EU CTISPhase 1/22 sites
Not yet recruitingBrazil
NCT07659704
CD19-Directed CAR-T Cell Therapy in Refractory Systemic Lupus Erythematosus
University of Sao Paulo
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govPhase 232 sites
RecruitingAustralia, Belgium, Chile, Israel, Japan, Netherlands
NCT07630714
A Study to Investigate Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Anifrolumab in Pediatric Participants 5 to < 18 Years of Age With Systemic Lupus Erythematosus
AstraZeneca
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govPhase 3133 sites
RecruitingArgentina, Austria, Australia, Belgium, Bulgaria, Brazil
NCT07691970
Rollover Study for Participants Who Have Completed a Previous Clinical Study With Anifrolumab (Saphnelo) and Clinically Benefited From Continued Treatment
AstraZeneca
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govPhase 134 sites
RecruitingAustralia, Belgium, Brazil, China, Germany, Spain
NCT07201558
Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants
AstraZeneca
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govPhase 122 sites
RecruitingChina
NCT07732309
A Study of ATG-201 in Adult Participants With Autoimmune Diseases
Antengene Biologics Limited
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govPhase 2140 sites
RecruitingArgentina, Australia, Bulgaria, Brazil, China, Colombia
NCT07409181
A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)
Boehringer Ingelheim
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govPhase 42 sites
RecruitingUnited States
NCT05559671
Safety of the Herpes Zoster Subunit Vaccine in Lupus
NYU Langone Health
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govNo phase0 sites
Not yet recruiting
NCT07901634
Association of Inflammatory Biomarkers and Ferritin With Severity of Pediatric Systemic Lupus Erythematosus Patients
Desy Wulandari
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT05567198
Gonadotropin-releasing Hormone Agonist (GnRHa) in Ovarian Preservation in SLE Subjects Receiving Cyclophosphamide as Determined by Questionnaires
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.govPhase 120 sites
RecruitingGermany, Spain, France, South Korea, Taiwan, United States
NCT06975787
Dose Escalation Study With Bispecific Antibodies in Adult Participants With Lupus Nephritis
Regeneron Pharmaceuticals
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.govPhase 127 sites
RecruitingAustralia, Bulgaria, Germany, Spain, France, Georgia
NCT06613360
A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus
Cullinan Therapeutics Inc.
Registry updated 26 Oct 2026
Registry record: ClinicalTrials.govPhase 117 sites
RecruitingGermany, Spain, United States
NCT06925542
A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease
CRISPR Therapeutics
Registry updated 26 Oct 2026
Registry record: ClinicalTrials.govPhase 351 sites
Not yet recruitingAustria, Belgium, Bulgaria, Czechia, Germany, Spain
2026-526419-13-00
Rollover Study for Participants Who Have Completed a Previous Clinical Study with Anifrolumab (Saphnelo) and Clinically Benefited from Continued Treatment.
AstraZeneca AB
Registry updated 26 Oct 2026
Registry record: EU CTISPhase 1/24 sites
RecruitingSpain
2026-527221-35-00
A Study of RO7871996 in Participants with Systemic Lupus Erythematosus
F. Hoffmann-La Roche AG
Registry updated 23 Oct 2026
Registry record: EU CTIS
The same sites as a list
- China159 open trials
- United States98 open trials
- France49 open trials
- Spain42 open trials
- Germany38 open trials
- Poland25 open trials
- Italy25 open trials
- Australia23 open trials
- Brazil22 open trials
- Romania19 open trials
- Japan19 open trials
- United Kingdom18 open trials
- Taiwan18 open trials
- Canada18 open trials
- Bulgaria16 open trials
- Belgium14 open trials
- Mexico13 open trials
- Argentina13 open trials
- Egypt13 open trials
- South Korea12 open trials
- Greece12 open trials
- Netherlands11 open trials
- Israel9 open trials
- Portugal9 open trials
- Hungary8 open trials
- Colombia8 open trials
- Peru7 open trials
- South Africa7 open trials
- Sweden7 open trials
- Chile7 open trials
- Czechia7 open trials
- Puerto Rico6 open trials
- Thailand6 open trials
- Philippines6 open trials
- Denmark5 open trials
- Georgia5 open trials
- Serbia5 open trials
- Hong Kong SAR China5 open trials
- Slovakia4 open trials
- Switzerland4 open trials
- Ukraine4 open trials
- Malaysia3 open trials
- Vietnam3 open trials
- India3 open trials
- Austria3 open trials
- Guatemala3 open trials
- Norway2 open trials
- Russia2 open trials
- Moldova2 open trials
- Pakistan2 open trials
- Lithuania2 open trials
- Singapore2 open trials
- Indonesia2 open trials
- Croatia1 open trials
- New Zealand1 open trials
- United Arab Emirates1 open trials
- Ireland1 open trials
- Costa Rica1 open trials
- Saudi Arabia1 open trials
- Kazakhstan1 open trials
- Kuwait1 open trials
- Oman1 open trials
- Qatar1 open trials
- Belarus1 open trials
- Panama1 open trials
- Algeria1 open trials
- Sri Lanka1 open trials
Who treats this
Institutions with trials or publications in this disease (OpenAlex, registries). Institutions only, no people.
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Brescia, Italy
15 trials · 45 publications · ROR
Chinese Academy of Medical Sciences & Peking Union Medical College
Beijing, China
0 trials · 202 publications · ROR
Cincinnati Children's Hospital Medical Center
Cincinnati, United States
6 trials · 41 publications · ROR
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
Barcelona, Spain
0 trials · 38 publications · ROR
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
São Paulo, Brazil
0 trials · 42 publications · ROR
Hospital Universitario de Gran Canaria Doctor Negrín
Las Palmas de Gran Canaria, Spain
0 trials · 43 publications · ROR
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
Mexico City, Mexico
0 trials · 67 publications · ROR
Manchester University NHS Foundation Trust
Manchester, United Kingdom
2 trials · 35 publications · ROR
Pfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research
Granada, Spain
0 trials · 41 publications · ROR
Research Institute of the McGill University Health Centre
Montreal, Canada
0 trials · 38 publications · ROR
The First Affiliated Hospital, Sun Yat-sen University
Guangzhou, China
7 trials · 38 publications · ROR
The University of Texas Southwestern Medical Center
Dallas, United States
1 trials · 74 publications · ROR
University of California, San Francisco
San Francisco, United States
4 trials · 108 publications · ROR
University of Occupational and Environmental Health Japan
Kitakyushu, Japan
0 trials · 65 publications · ROR
University of Oklahoma Health Sciences Center
Oklahoma City, United States
0 trials · 39 publications · ROR
What changed in the last 7 days
Registry facts, one per line, newest first.
Phase changed: No phase → Phase 2/3
A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101
NCT07403188 · Phase 2/3 · Germany, United States
Source: ClinicalTrials.gov
Results card
Trials that finished or stopped in the last 3 years, with the reason the registry gives and linked publications.
Phase 1/2Ended 24 Sept 2026
Completed21 participants
NCT05798117
An Open-label, Study to Assess Safety, Efficacy and Cellular Kinetics of YTB323 in Severe, Refractory Systemic Lupus Erythematosus
No phaseEnded 31 Jul 2026
Completed14 participants
NCT05818254
The HOP-STEP Intervention: Improving Maternal Health in Women With Lupus sIRB
Phase 2Ended 13 Jul 2026
Completed48 participants
NCT05268289
Study of efficacy and safety of LNP023 in participants with active lupus nephritis Class III-IV, +/- V
Phase 1Ended 8 Jul 2026
Completed14 participants
NCT06064929
A Study to Learn More About the Safety and Effects of Felzartamab in Adults With Lupus Nephritis Aged 18 to 75 Years Old
Phase 2Ended 2 Jul 2026
Completed123 participants
NCT05796206
A Phase 2 Clinical Study of MIL62 in Systemic Lupus Erythematosus
Phase 2/3Ended 22 Jun 2026
Completed30 participants
2023-507867-20-00
A randomized trial to investigate the reset of humoral autoimmunity by combining belimumab with rituximab in severe systemic lupus erythematosus
Phase 3Ended 22 Jun 2026
No phaseEnded 10 Jun 2026
Completed100 participants
NCT07840573
Feasibility and Performance of a Structured Video Telemedicine Program in Patients With Systemic Lupus Erythematous
Phase 1/2Ended 8 Jun 2026
Early Phase 1Ended 6 Jun 2026
Completed3 participants
NCT06653556
A Study of LCAR-AIO in Subjects With Relapsed/Refractory Systemic Lupus Erythematosus
Phase 1Ended 14 Apr 2026
Phase 1Ended 13 Apr 2026
Phase 1Ended 1 Mar 2026
Completed3 participants
NCT06150651
Safety of PiggyBac Transposon CAR T-cells Targeting CD-19 in Refractory Lupus.
Phase 2Ended 28 Feb 2026
Completed111 participants
NCT03527472
Memantine for the Treatment of Cognitive Impairment in Systemic Lupus Erythematosus
Phase 2Ended 27 Feb 2026
Completed186 participants
NCT05856448
A Study Evaluating the Effects of GLPG3667 Administered as Oral Treatment in Adult Participants With Active Systemic Lupus Erythematosus
No phaseEnded 20 Feb 2026
Completed149 participants
NCT06796569
Systemic Immune Inflammatory Index in Systemic Lupus Erythematosus
Phase 2Ended 3 Feb 2026
Completed81 participants
NCT02633163
Phase 2 Trial of Mesenchymal Stem Cells in Systemic Lupus Erythematosus (MiSLE)
No phaseEnded 23 Jan 2026
Completed88 participants
NCT07267091
The Burden of Lupus in Canada From a Patient Perspective: A Canadian Real-World PROxy Study
Phase 1Ended 7 Jan 2026
Completed48 participants
NCT06144710
SG301-SC Injection Safety Study in Subjects With Systemic Lupus Erythematosus
No phaseEnded 31 Dec 2025
Completed884 participants
NCT07123220
Prognostic Factors for Fatigue in Patients With Systemic Lupus Erythematosus
No phaseEnded 31 Dec 2025
Completed36 participants
NCT06720584
Whole Health Empowerment for Endotypes of Lupus: Improving Quality of Life in SLE
No phaseEnded 31 Dec 2025
Completed56 participants
NCT07031674
Comparing Efficacy and Safety of Telitacicept and Belimumab in Lupus Nephritis: A Retrospective Multicenter Cohort Study.
Phase 1/2Ended 22 Dec 2025
No phaseEnded 15 Dec 2025
No phaseEnded 1 Dec 2025
Completed130 participants
NCT07024082
Water-based Liuzijue Exercise on Childhood-onset Systemic Lupus Erythematosus
No phaseEnded 30 Nov 2025
Phase 1Ended 21 Nov 2025
Phase 1Ended 14 Nov 2025
Completed16 participants
NCT05687526
A Study of Telitacicept in Subjects With Childhood-onset Systemic Lupus Erythematosus
No phaseEnded 2 Nov 2025
Phase 1Ended 27 Oct 2025
Completed125 participants
NCT05411016
A Study of KK4277 in Healthy Volunteers and Patients With Systemic Lupus Erythematosus and Cutaneous Lupus Erythematosus
No phaseEnded 21 Oct 2025
Completed325 participants
NCT04902807
Conception of a Diagnosis, Prognosis and Therapeutic Decision Tool for Patients With Autoimmunity and Inflammation
No phaseEnded 8 Oct 2025
Completed6 participants
NCT05747651
3TR (Taxonomy, Treatment, Targets and Remission) Systemic Lupus Erythematosus Study Protocol 2
Phase 2Ended 8 Oct 2025
Completed10 participants
NCT05879718
A Phase 2 Multicenter Study to Evaluate PF-06823859 in Adult Participants With Active CLE or SLE With Cutaneous Manifestations
Phase 2Ended 30 Sept 2025
Completed93 participants
NCT01649765
Pediatric Lupus Trial of Belimumab Plus Background Standard Therapy
No phaseEnded 19 Sept 2025
Completed637 participants
NCT06759519
Clinical and Demographic Features of Patients With Moderate to Severe Active Systemic Lupus Erythematosus in Russia
Phase 2Ended 1 Sept 2025
Completed73 participants
NCT05810948
A Study to Assess Effectiveness and Safety of Efgartigimod in Chinese Patients With Lupus Nephritis (ZL-1103-013)
No phaseEnded 13 Aug 2025
Completed69 participants
NCT04645589
Evaluating the Safety of Myfortic (Mycophenolate Sodium) in Patients With Lupus Nephritis
Phase 2Ended 12 Aug 2025
Completed131 participants
NCT07281105
EG-501 for Cognitive Impairment in Neuropsychiatric SLE (NPSLE): Efficacy and Safety Study
No phaseEnded 31 Jul 2025
Phase 2Ended 31 Jul 2025
No phaseEnded 20 Jul 2025
Completed35 participants
NCT03915652
Addressing Disparities in Lupus Care Through an Integrated Care Management Program
Phase 2Ended 15 Jul 2025
Completed87 participants
NCT04564339
Study of Ravulizumab in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)
No phaseEnded 2 Jul 2025
Completed10 participants
NCT06556992
Fitness Integrative Training for Pediatric Rheumatology Disorders
Phase 2/3Ended 30 Jun 2025
Completed69 participants
2023-505520-61-00
A clinical study of MK-6194 for the treatment of Systemic Lupus Erythematosus (SLE) (MK-6194-006)
No phaseEnded 27 Jun 2025
Completed124 participants
NCT00582881
Characteristics and Disease Progression of Mixed Connective Tissue Disease and Systemic Lupus Erythematosus
No phaseEnded 24 Jun 2025
Completed561 participants
NCT06485674
Long-Term Organ Damage: Anifrolumab Versus Real-World Standard of Care in Adult Patients With Active Systemic Lupus Erythematosus
No phaseEnded 20 Jun 2025
Completed176 participants
NCT01180361
Atherosclerosis in Rheumatoid Arthritis and Lupus: Restoring Cholesterol Balance
No phaseEnded 10 Jun 2025
Phase 3Ended 10 Jun 2025
Completed277 participants
NCT04931563
Anifrolumab Asian PhIII Efficacy Study for Systemic Lupus Erythematosus (SLE)
No phaseEnded 5 Jun 2025
Phase 3Ended 4 Jun 2025
Completed33 participants
NCT05001737
Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE
No phaseEnded 7 May 2025
Completed59 participants
NCT07398885
Assessing the Impact of Herbal Supplement on Fatigue and Disease Activity in SLE: Results From an 8-Week Randomized Trial
Phase 1Ended 5 May 2025
Phase 2Ended 28 Apr 2025
Completed107 participants
NCT03656562
Study the Efficacy and Safety of VAY736 and CFZ533 in SLE Patients
Phase 2/3Ended 16 Apr 2025
Phase 1/2Ended 1 Apr 2025
Completed26 participants
NCT05638802
A Study of DS-7011a in Patients With Systemic Lupus Erythematosus
Phase 1Ended 1 Apr 2025
Completed40 participants
NCT05866861
A Study in Participants With Mild-to-moderate Systemic Lupus Erythematosus
No phaseEnded 30 Mar 2025
Phase 2Ended 21 Mar 2025
Completed261 participants
NCT03920267
Long-Term Safety and Efficacy Study of Deucravacitinib in Participants With Systemic Lupus Erythematosus
No phaseEnded 28 Feb 2025
Completed3138 participants
NCT01729455
Safety and Effectiveness of BENLYSTA (Belimumab) in Systemic Lupus Erythematosus (SLE) Registry
Not medical advice. fetched 4 Nov 2026