Primary biliary cholangitis: trials for referral
45 open trials in the registries we read. Each row links to its registry record.
Registry data only. Frontlight does not judge whether a patient can take part: the trial team decides.
Where the open trials are
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45 trials shown
Phase 3220 sites
RecruitingArgentina, Austria, Australia, Belgium, Canada, Switzerland
NCT06051617
Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis
Gilead Sciences
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govPhase 32 sites
RecruitingChina
NCT07296458
FIREFLY Trial: Fenofibrate Intervention---Randomized Evaluation in First-Line PBC Therapy
Xijing Hospital of Digestive Diseases
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govPhase 31 site
RecruitingChina
NCT02823366
Fenofibrate for Patients With Primary Biliary Cirrhosis Who Had An Inadequate Response to Ursodeoxycholic Acid
Xijing Hospital of Digestive Diseases
Registry updated 30 Oct 2026
Registry record: ClinicalTrials.govNo phase0 sites
Not yet recruiting
NCT07906639
A Study of Fatigue, Itching and Daily Activities in People With Primary Biliary Cholangitis Starting Elafibranor
Ipsen
Registry updated 30 Oct 2026
Registry record: ClinicalTrials.govPhase 2/31 site
RecruitingChina
NCT06365424
Fenofibrate in Patients With Primary Biliary Cholangitis (PBC)
Xijing Hospital of Digestive Diseases
Registry updated 30 Oct 2026
Registry record: ClinicalTrials.govPhase 2/32 sites
By invitation onlyChina
NCT06591468
A Multicenter, Randomized, Controlled Trial of Prednisone Combined With Ursodeoxycholic Acid in the Treatment of Primary Biliary Cholangitis With Moderate to Severe Interface Hepatitis Characteristics
Han Ying
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT01793168
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
Sanford Health
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govPhase 24 sites
RecruitingUnited States
NCT07841977
Study of Seladelpar and Cilofexor in Participants With Primary Biliary Cholangitis
Gilead Sciences
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.govPhase 3191 sites
RecruitingArgentina, Australia, Belgium, Bulgaria, Brazil, Canada
NCT06016842
A Long-Term Study of Elafibranor in Adult Participants With Primary Biliary Cholangitis
Ipsen
Registry updated 23 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT07556913
Elafibranor Pregnancy Surveillance Program: A Study to Evaluate the Safety of Elafibranor During Pregnancy
Ipsen
Registry updated 23 Oct 2026
Registry record: ClinicalTrials.govPhase 30 sites
Not yet recruiting
NCT07860710
J-LINX: Japan LINerixibat eXtension Study
GlaxoSmithKline
Registry updated 6 Oct 2026
Registry record: ClinicalTrials.govPhase 21 site
Not yet recruitingUnited States
NCT07843420
Nemolizumab for the Treatment of Moderate to Severe Chronic Hepatic Pruritus
Mayo Clinic
Registry updated 28 Sept 2026
Registry record: ClinicalTrials.govPhase 31 site
RecruitingUnited States
NCT07424677
Study of Saroglitazar Magnesium for PBC Patients With Incomplete Response or Intolerant to UDCA Therapy
Zydus Therapeutics Inc.
Registry updated 15 Sept 2026
Registry record: ClinicalTrials.govPhase 11 site
RecruitingUnited States
NCT06825559
Evaluate PK & Safety of Saroglitazar in Subjects With Moderate Hepatic Impairment Due to Cholestatic Liver Disease
Zydus Therapeutics Inc.
Registry updated 14 Sept 2026
Registry record: ClinicalTrials.govPhase 1/21 site
Not yet recruitingChina
NCT07795151
Phase I/II Trial of Human Umbilical Cord Mesenchymal Stromal Cells for UDCA-Refractory Primary Biliary Cholangitis
Beijing 302 Hospital
Registry updated 31 Aug 2026
Registry record: ClinicalTrials.govNo phase1 site
Not yet recruitingChina
NCT07733882
Study on Clinical and Pathological Features of Primary Biliary Cholangitis and Risk Factors Related to Disease Progression
Beijing Municipal Administration of Hospitals
Registry updated 4 Aug 2026
Registry record: ClinicalTrials.govPhase 344 sites
RecruitingBulgaria, Estonia, Spain, France, Greece, Croatia
NCT07216235
Long-Term Study to Evaluate the Safety and Efficacy in Participants With Primary Biliary Cholangitis of Saroglitazar Magnesium-V on Clinical Outcomes
Zydus Therapeutics Inc.
Registry updated 4 Aug 2026
Registry record: ClinicalTrials.govNo phase8 sites
RecruitingBelgium, Germany, France, Italy, Netherlands
NCT06723275
LEOPARD Prospective Validation Cohort 1
Assistance Publique - Hôpitaux de Paris
Registry updated 29 Jul 2026
Registry record: ClinicalTrials.govNo phase53 sites
RecruitingAustria, Belgium, Germany, Spain, France, Italy
NCT06675604
LEOPARD Training and Validation Data Collection Study
Assistance Publique - Hôpitaux de Paris
Registry updated 29 Jul 2026
Registry record: ClinicalTrials.govPhase 342 sites
RecruitingChina
NCT07282353
A Study of CS0159 in Patients With PBC With Inadequate Response or Intolerance to UDCA
Cascade Pharmaceuticals, Inc
Registry updated 8 Jul 2026
Registry record: ClinicalTrials.govPhase 21 site
Not yet recruitingChina
NCT07678645
The Safety and Efficacy of Upadacitinib in Refractory Autoimmune Related Cholangitis and Atopic Dermatitis With Moderate to Severe Itching
RenJi Hospital
Registry updated 1 Jul 2026
Registry record: ClinicalTrials.govNo phase1 site
By invitation onlyUnited States
NCT07631442
Using Digital Health Technology to Monitor Patients With Primary Biliary Cholangitis (PBC)
Stanford University
Registry updated 11 Jun 2026
Registry record: ClinicalTrials.govNo phase11 sites
RecruitingAustria
NCT07598669
Austrian PBC Registry
Medical University of Vienna
Registry updated 20 May 2026
Registry record: ClinicalTrials.govNo phase1 site
Not yet recruitingBelgium
NCT07319169
The Value of Spleen Stiffness Measurement in Patients With PBC
Universitair Ziekenhuis Brussel
Registry updated 1 May 2026
Registry record: ClinicalTrials.govNo phase21 sites
Not yet recruitingSwitzerland, Germany
NCT07549607
Clinical Characterization of Patients With Primary Biliary Cirrhosis Treated With Seladelpar in the Real-life Setting
University of Leipzig
Registry updated 24 Apr 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingSouth Korea
NCT06519162
Liver-gut Axis Study Through Identification of Liver Disease-specific Microbiome
Chungnam National University Hospital
Registry updated 20 Mar 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingChina
NCT07449793
Biochemical Response and Clinical Outcomes in Patients With PBC
RenJi Hospital
Registry updated 4 Mar 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT03445585
Biobank for Cholestatic Liver Diseases.
Mayo Clinic
Registry updated 17 Feb 2026
Registry record: ClinicalTrials.govPhase 31 site
RecruitingChina
NCT06755151
Fenofibrate in Primary Biliary Cholangitis: a Real World Study
Xijing Hospital of Digestive Diseases
Registry updated 8 Jan 2026
Registry record: ClinicalTrials.govPhase 31 site
RecruitingChina
NCT06755541
Fenofibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cholangitis: a Real World Study
Xijing Hospital of Digestive Diseases
Registry updated 8 Jan 2026
Registry record: ClinicalTrials.gov
The same sites as a list
- China16 open trials
- United States11 open trials
- Spain8 open trials
- France6 open trials
- Italy6 open trials
- Belgium5 open trials
- Germany4 open trials
- South Korea3 open trials
- Austria3 open trials
- Poland3 open trials
- Switzerland3 open trials
- Greece3 open trials
- Denmark3 open trials
- Netherlands3 open trials
- Mexico2 open trials
- Argentina2 open trials
- Israel2 open trials
- Australia2 open trials
- Portugal2 open trials
- Slovakia2 open trials
- Taiwan1 open trials
- Canada1 open trials
- Hong Kong SAR China1 open trials
- Hungary1 open trials
- United Kingdom1 open trials
- Singapore1 open trials
- Romania1 open trials
- Brazil1 open trials
- Czechia1 open trials
- Chile1 open trials
- Malaysia1 open trials
- New Zealand1 open trials
- Lithuania1 open trials
- Colombia1 open trials
- Thailand1 open trials
- Ireland1 open trials
- Estonia1 open trials
- Bulgaria1 open trials
- Croatia1 open trials
- Latvia1 open trials
Who treats this
Institutions with trials or publications in this disease (OpenAlex, registries). Institutions only, no people.
Amsterdam Gastroenterology Endocrinology Metabolism
Amsterdam, Netherlands
0 trials · 12 publications · ROR
Amsterdam UMC Location University of Amsterdam
Amsterdam, Netherlands
0 trials · 21 publications · ROR
Amsterdam UMC Location Vrije Universiteit Amsterdam
Amsterdam, Netherlands
0 trials · 10 publications · ROR
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
Milan, Italy
3 trials · 29 publications · ROR
Cambridge University Hospitals NHS Foundation Trust
Cambridge, United Kingdom
0 trials · 13 publications · ROR
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
Madrid, Spain
0 trials · 23 publications · ROR
Chinese Academy of Medical Sciences & Peking Union Medical College
Beijing, China
0 trials · 23 publications · ROR
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
Barcelona, Spain
0 trials · 17 publications · ROR
First Affiliated Hospital of Kunming Medical University
Kunming, China
0 trials · 11 publications · ROR
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, Italy
3 trials · 10 publications · ROR
GlaxoSmithKline Research & Development Limited (United Kingdom)
London, United Kingdom
0 trials · 10 publications · ROR
Hospital das Clínicas da Universidade Federal de Minas Gerais
Belo Horizonte, Brazil
0 trials · 17 publications · ROR
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
Mexico City, Mexico
0 trials · 13 publications · ROR
National Clinical Research Center for Digestive Diseases
Beijing, China
0 trials · 24 publications · ROR
National Institute for Health and Care Research
London, United Kingdom
0 trials · 16 publications · ROR
Newcastle upon Tyne Hospitals NHS Foundation Trust
Newcastle upon Tyne, United Kingdom
0 trials · 13 publications · ROR
NIHR Birmingham Biomedical Research Centre
Birmingham, United Kingdom
0 trials · 28 publications · ROR
NIHR Newcastle Biomedical Research Centre
Newcastle upon Tyne, United Kingdom
0 trials · 24 publications · ROR
The University of Texas at San Antonio Health Science Center
San Antonio, United States
0 trials · 22 publications · ROR
The University of Texas Southwestern Medical Center
Dallas, United States
0 trials · 40 publications · ROR
University Hospitals Birmingham NHS Foundation Trust
Birmingham, United Kingdom
1 trials · 14 publications · ROR
University of California Davis Medical Center
Sacramento, United States
6 trials · 41 publications · ROR
What changed in the last 7 days
Registry facts, one per line, newest first.
No registry change in the last 7 days.
Results card
Trials that finished or stopped in the last 3 years, with the reason the registry gives and linked publications.
Phase 1/2Ended 9 Sept 2026
Phase 2Ended 23 Jul 2026
Phase 3Ended 16 Jun 2026
Completed92 participants
NCT06383403
A Study of Elafibranor in Adults With Primary Biliary Cholangitis and Inadequate Response or Intolerance to Ursodeoxycholic Acid.
Phase 3Ended 6 May 2026
No phaseEnded 23 Feb 2026
Completed30 participants
NCT07049887
A Study Describing Scratch and Sleep Patterns in Patients With Primary Biliary Cholangitis (Luminaria)
Phase 1/2Ended 30 Jan 2026
Completed42 participants
NCT05104853
Study to Evaluate the Safety, Tolerability, PDs, and Efficacy of CNP-104 in Subjects With Primary Biliary Cholangitis
No phaseEnded 24 Oct 2025
Completed220 participants
NCT07784881
Deciphering the Self-antigen Specific T Cell Signature of Autoimmune Liver Diseases
Phase 3Ended 15 Oct 2025
Phase 2Ended 14 Oct 2025
Phase 2Ended 1 Sept 2025
Completed72 participants
NCT05239468
Study of OCA in Combination With BZF Evaluating Efficacy, Safety and Tolerability in Participants With PBC
Early Phase 1Ended 18 Aug 2025
Completed30 participants
NCT06591455
A Pilot Study of Fenofibrate and Ursodeoxycholic Acid in the Treatment of Newly Diagnosed Primary Biliary Cholangitis
No phaseEnded 31 Jul 2025
No phaseEnded 16 Jul 2025
Phase 1Ended 3 Jun 2025
Completed24 participants
NCT06888115
A Study of the Pharmacokinetics and Safety of CS0159 in Subjects With Hepatic Injury
Phase 2/3Ended 7 May 2025
Completed196 participants
NCT05133336
Saroglitazar Magnesium for Treatment of Primary Biliary Cholangitis
Phase 1Ended 23 Apr 2025
Phase 1Ended 9 Apr 2025
Phase 1Ended 27 Feb 2025
Completed24 participants
NCT04950764
An Open-Label Study Following Oral Dosing of Seladelpar to Participants With Primary Biliary Cholangitis (PBC) and Hepatic Impairment (HI)
No phaseEnded 15 Feb 2025
Completed57 participants
NCT03188146
Performance of Scoring Systems in Chinese Patients With Primary Biliary Cholangitis (PBC) on Ursodeoxycholic Acid
No phaseEnded 23 Jan 2025
Completed711 participants
NCT02932449
A 5-year Longitudinal Observational Study of Patients With Primary Biliary Cholangitis
Phase 3Ended 20 Dec 2024
Completed238 participants
NCT04950127
Global Linerixibat Itch Study of Efficacy and Safety in Primary Biliary Cholangitis (PBC) (GLISTEN)
No phaseEnded 1 Dec 2024
Completed825 participants
NCT05786482
Evidence Based Mental Wellness Programming Online for Adults Across Chronic Physical Conditions
Phase 2Ended 5 Sept 2024
Completed62 participants
NCT05525520
Study to Evaluate EP547 in Subjects With Cholestatic Pruritus Due to Primary Biliary Cholangitis or Primary Sclerosing Cholangitis
Phase 2Ended 2 Jul 2024
Completed76 participants
NCT05014672
A Trial of Setanaxib in Patients With Primary Biliary Cholangitis (PBC) and Liver Stiffness
No phaseEnded 30 Jun 2024
Phase 3Ended 29 Apr 2024
Completed100 participants
NCT06715319
Obeticholic Acid Versus Placebo, in Combination with Ursodeoxycholic Acid in Patients with Primary Biliary Cirrhosis
Phase 3Ended 9 Apr 2024
Completed108 participants
NCT05450887
Efficacy and Safety of Obeticholic Acid in the Treatment of Primary Biliary Cholangitis
Phase 2Ended 13 Mar 2024
Completed98 participants
NCT05190523
Study to Evaluate the Safety and Efficacy of ASC42 Tablets in Subjects With Primary Biliary Cholangitis
Phase 2Ended 1 Jan 2024
No phaseEnded 31 Dec 2023
Completed34 participants
NCT04791527
Online Wellness Intervention for Primary Biliary Cholangitis (PBC)
No phaseEnded 31 Dec 2023
Completed60 participants
NCT06309589
The Effectiveness of Combining Ursodeoxycholic Acid With Vitamin D in Treating Patients With Primary Biliary Cholangitis
Not medical advice. fetched 4 Nov 2026