Sarcoma: who works on it

One card per institution. Pick a target or a country to narrow the list.

• All targets
• KRAS 10
• TP53 1
• PD-1 19
• PD-L1 9
• PI3K 0
• AKT 0
• NTRK 2
• mTOR 0
• STAT3 0
• MAPK 0
• CTNNB1 0
• MDM2 2
• BRAF 3
• MYC 0
• RAS 3
• ERK 0
• JNK 0
• VEGF 3
• ALK 2
• B7-H3 10
• STING 1
• CDK4/6 3
• EGFR 1
• JAK 1
• PARP 4
• YAP 0
• IDH 2
• FGFR 2
• HER2 5
• MEK 2
• CTLA-4 5
• NRAS 0
• GPX4 0
• HIF-1 0
• PTEN 0
• EZH2 0
• PPAR 0
• METTL3 1
• NF1 5
• AMPK 0
• GPC3 5
• PDGFR 3
• ABL1 0
• CD47 0
• COX-2 0
• ROS1 2
• AXL 0
• CDKN2A 0
• CXCR4 0
• IL-15 4
• MMP-9 0
• PRAME 1
• PSMA 0
• RET 0
• BCL-2 0
• BRCA2 1
• CD19 2
• FLT3 0
• FTO 0
• HDAC 0

9 of 9+ institutions, ordered by recent publications and open trials. This is not a ranking of quality.

Funded research projects that name this disease in their title, terms or summary and have not ended yet: who is funded, where, how much and until when. Organisations only; the funder's page has the details.

• NIH NEI · R43

  Novel gene mutation agnostic small molecule to treat retinitis pigmentosa

  Mitochem Therapeutics Inc.· Charleston, United States· US$320,790 awarded in fiscal year 2026· until Aug 2027

• NIH NCI · F31

  Assessing autophagic dependencies in the context of RAS inhibition in pancreatic ductal adenocarcinoma

  Univ of North Carolina Chapel Hill· Chapel Hill, United States· US$37,011 awarded in fiscal year 2026· until Sept 2029

• NIH NIA · R01

  Synapse repair in Alzheimer's disease and related dementias

  Buck Institute for Research on Aging· Novato, United States· US$785,081 awarded in fiscal year 2026· until Jul 2031

• NIH NINDS · R43

  Development of an Anti-Nerve Growth Factor Active Immunotherapy for Difficult-to-Manage Pain

  Twilight Bioscience, Inc.· Topsfield, United States· US$350,188 awarded in fiscal year 2026· until Aug 2028

• NIH NCI · R16

  Mechanisms of lymphoma cell dissemination to the brain

  North Park University· Chicago, United States· US$162,527 awarded in fiscal year 2026· until Aug 2030

• European Commission (Horizon Europe) · HORIZON-RIA

  immunoTHErapies targeting neOgenes in paeDiatric and adOlescent saRcomAs (THEODORA)

  Institut Curie· Paris, France· EU contribution €8,712,800· until Feb 2032· 5 countries

• European Commission (Horizon Europe) · HORIZON-ERC

  Primary bone cancer scaffolds as controlled release non-viral gene delivery platforms (PANACEA)

  Royal College of Surgeons in Ireland· Dublin 2, Ireland· EU contribution €2,302,626· until May 2031

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Self-Assembling, Self-Monitoring, Multi-Stimuli-Responsive Implants for the Minimally Invasive Treatment of Critical-Size Defects (Morphogenesis)

  Fundacion Imdea Materiales· Getafe, Spain· EU contribution €194,075· until Mar 2028

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Investigating the role of RNA-binding proteins in telomere replication stress and alternative lengthening of telomeres (RBPandALT)

  The Francis Crick Institute Limited· London, United Kingdom· EU contribution €260,348· until Mar 2028

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-EIC-ACC

  Pioneering antibody-drug conjugates targeting the tumour microenvironment to deliver transformative new therapies in oncology (ONCO-DART)

  Oncomatryx Biopharma Sa· Derio, Spain· EU contribution €2,499,376· until Oct 2027

  The disease is named only in the funder's project summary, not in the title.

10 of 1,624 running projects, newest first. Listed amounts together: US$944.4m + €86.8m.

Sources: NIH RePORTER (U.S. National Institutes of Health, public domain) and CORDIS (European Commission, CC BY 4.0). Changes: filtered by disease, organisations matched to ROR.

Trials whose registry record says individual participant data (IPD) will be shared.

• A First-in-Human Study Investigating BG-85738 Alone or in Combination With Other Antitumor Agents in Patients With Advanced or Metastatic Solid Tumors With Rat Sarcoma Virus (RAS) Mutations

  NCT07746141· BeOne Medicines· Source

Find publications on this disease by a MeSH method term, for example a sequencing or imaging method.

• Single-Cell Analysis 41
• Organoids 10
• Mendelian Randomization Analysis 2
• CRISPR-Cas Systems 11
• Gene Expression Profiling 99
• Sequence Analysis, RNA 21
• Whole Genome Sequencing 4
• Exome Sequencing 14
• Proteomics 31
• Metabolomics 7
• Mass Spectrometry 5
• Flow Cytometry 52
• Immunohistochemistry 186
• Liquid Biopsy 12
• Circulating Tumor DNA 19
• Xenograft Model Antitumor Assays 153
• Positron-Emission Tomography 19
• Magnetic Resonance Imaging 198
• Machine Learning 29
• Deep Learning 16
• Cohort Studies 30
• Genome-Wide Association Study 2

• Ewing Sarcoma PDX Models.

  Methods Mol Biol, Jan 2027

• Using Zebrafish Larvae as a Xenotransplantation Model to Study Ewing Sarcoma.

  Methods Mol Biol, Jan 2027

• Chorioallantoic Membrane Assay to Assess Primary and Metastatic Tumor Growth in Ewing Sarcoma.

  Methods Mol Biol, Jan 2027

• Orthotopic Implants in Mice.

  Methods Mol Biol, Jan 2027

• Tumor Growth Analysis of Ewing Sarcoma Cell Lines Using Subcutaneous Xenografts in Mice.

  Methods Mol Biol, Jan 2027

• PRMT1 blockade reverts resistance to KRAS (G12C) inhibition through modulating ferroptosis signalling.

  Int J Oncol, Nov 2026

• AXL-directed antibody-drug conjugate therapy in soft-tissue sarcoma.

  J Hematol Oncol, Oct 2026

• FTO Promotes Osteosarcoma Progression via YAP and Reduces Cisplatin Sensitivity.

  Front Biosci (Landmark Ed), Oct 2026

• NAPRT Expression and Epigenetic Regulation in Pediatric Rhabdomyosarcoma as a Potential Biomarker for NAMPT Inhibition.

  Mol Cancer Ther, Oct 2026

• Gene regulatory elements determine efficacy of BCMA-targeted CAR-T cell products.

  J Immunother Cancer, Sept 2026

  Marcela V Maus

See which targets of this disease your abstract mentions, and go to the people working on them.