Dent Neurological Institute

The trials here

What the 8 trials at this site are about, from their registry records.

Conditions

• Multiple sclerosis2 trials
• Parkinson disease2 trials
• Depression1 trial
• Essential tremor1 trial
• Huntington's disease1 trial
• Migraine1 trial

Phase

• Phase 23 trials
• Phase 33 trials

Status

• Active, not recruiting4 trials
• Recruiting3 trials
• Completed1 trial

Lead sponsor

• Hoffmann-La Roche5 trials
• Children's Hospital Medical Center, Cincinnati1 trial
• Jazz Pharmaceuticals1 trial
• LivaNova1 trial

Running trials

• Recruiting

  A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

  NCT07174310· Phase 3· Hoffmann-La Roche· Source

• Recruiting

  Responding With Evidence and Access for Childhood Headaches

  NCT05889624· Children's Hospital Medical Center, Cincinnati· Source

  Contact: Andrea Bryan

• Active, not recruiting

  GENERATION HD2. A Study to Evaluate the Safety, Biomarkers, and Efficacy of Tominersen Compared With Placebo in Participants With Prodromal and Early Manifest Huntington's Disease

  NCT05686551· Phase 2· Hoffmann-La Roche· Source

• Active, not recruiting

  A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease

  NCT04777331· Phase 2· Hoffmann-La Roche· Source

• Active, not recruiting

  A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Relapsing Multiple Sclerosis (RMS)

  NCT04544436· Phase 3· Hoffmann-La Roche· Source

• Active, not recruiting

  A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Ocrelizumab in Adult Participants With Primary Progressive Multiple Sclerosis

  NCT04544449· Phase 3· Hoffmann-La Roche· Source

• Recruiting

  A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

  NCT03887715· LivaNova· Source

  Contact: Michelle Rainka, PharmD

Recruiting at the same time

How many trials recruit for the same indication here at once. A count, not a rating.

• Depression1 recruiting
• Migraine1 recruiting
• Parkinson disease1 recruiting

Closed trials

• Completed

  A Study To Assess the Safety and Efficacy of JZP385 in the Treatment of Adults With Moderate to Severe Essential Tremor (ET)

  NCT05122650· Phase 2· Jazz Pharmaceuticals· Source