Taking people in BelgiumPhase 2
PET scan tracer for advanced thyroid and head and neck cancers
Tests a PET scan tracer to see if it shows cancer spots in adults.
Key facts
- Who runs it
- Universitair Ziekenhuis Gent
- Where
- Gent, BelgiumSee the site
- Trial code
- Registry title
- [18F]AlF-PSMA-11 PET in advanced thyroid and head and neck carcinoma
- Status
- Recruiting
- Phase
- Phase 2
- People taking part
- 40 people, planned
- Started
- 1 Feb 2024
- Expected to end
- 24 Nov 2026
- Type of study
- Interventional
- Record updated
- 7 October 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with advanced thyroid or head and neck cancer who have at least one measurable lesion. It tests whether a PET scan tracer called [18F]AlF-PSMA-11 shows up in the lesions.
- Age
- 18 years or older
- Sex
- All sexes can join.
- Disease stage
- Advanced thyroid carcinoma or head and neck squamous cell carcinoma, with at least 1 measurable lesion of 1.0 cm (0.4 in) or more on medical imaging.
Main reasons for not taking part
- Pregnant or breastfeeding women
- Women who might be pregnant and refuse a pregnancy test at screening
- Known allergy to [18F]AlF-PSMA-11 or the substances used with it
The registry criteria, word for word
Show all 6 criteriaShow less
Who can take part
- 18 years of age or older
- willing and mentally and legally capable of providing written informed consent
- have ≥ 1 measurable lesion of interest of ≥ 1.0 cm on medical imaging
Who cannot take part
- Patients with known hypersensitivity to the [¹⁸F]AlF-PSMA-11 or used excipients
- potentially pregnant female patients refusing pregnancy testing at screening
- pregnant or breastfeeding female patients
Where in Belgium
- Universitair Ziekenhuis GentGent, BelgiumTaking people
About the trial
What the trial wants to find out
demonstrate uptake of [¹⁸F]AlF-PSMA-11 in lesions on PET.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record
Print a page for my doctorData and sources
- Registry record
- Listed on the EU's official list of trials (CTIS).
- Official title
- Prostate-specific membrane antigen in thyroid and head and neck carcinoma: On the utility of [18F]AlF-PSMA-11 PET in advanced disease
- Plain-language title
- PET scan tracer for advanced thyroid and head and neck cancersGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 9 November 2026.
- Record updated
- 7 October 2025