Testing blood tests and MRI scans to better detect ovarian cancer
Studies blood samples and imaging scans to improve diagnosis of ovarian cancer in adults.
Key facts
- Who runs it
- Aarhus University
- Where
- Aarhus N, DenmarkSee the site
- Trial code
- Registry title
- IMPROCAS - Improved Prediction of Ovarian Cancer Surgery
- Status
- Recruiting
- Phase
- Phase 2
- People taking part
- 40 people, planned
- Started
- 1 Mar 2024
- Expected to end
- 1 Aug 2029
- Type of study
- Interventional
- Record updated
- 30 May 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for women aged 18 to 85 with suspected epithelial ovarian cancer who are referred to the gynaecology department at AUH and understand Danish.
- Age
- 18 to 85 years
- Sex
- Women only
- Disease stage
- Suspected epithelial ovarian cancer, not yet confirmed.
Main reasons for not taking part
- Cannot have an MRI scan with contrast (for example a pacemaker, metal implants, claustrophobia, or eGFR less than 30 ml/min/1.73m2)
- Severe unstable asthma
- Allergy to pyruvate
- Pregnancy
- Another cancer, or a returning cancer, within the last 3-5 years (except benign basal cell carcinoma)
The registry criteria, word for word
Show all 9 criteriaShow less
Who can take part
- Suspected epithelial ovarian cancer (and referred to dept. of Gynaecology and Obstetrics, AUH)
- Understanding Danish
- Age 18 – 85 years
Who cannot take part
- Severe renovascular disease
- Any other malign disease or recidiv of a former malign disease present within the last 3-5 years (except benign basal basocelluar carcinoma (BBC))
- Allergy to pyruvate
- Contraindications for MRI with contrast: - eGFR less than 30 ml/min/1.73m2 - Severe unstable asthma - Pacemaker, implantable cardiac defibrillator, neurostimulator or cochlear implant - Metal foreign bodies such as fragments and irremovable piercings - Unsafe medical implants (safety of heart valves, hips and the like must be confirmed) - Claustrophobia - Largest circumference including arms > 160 cm
- Substantial cognitive disability that would influence the patients’ ability to either give truly informed consent or listen to / comply with safety-related instructions
- Pregnancy
Where in Denmark
- Aarhus UniversitetAarhus N, DenmarkTaking people
About the trial
What the trial wants to find out
The aim of this project is to investigate nuclear magnetic resonance (NMR)-derived metabolomics from blood samples, functional and metabolic MRI techniques and their ability to improve ovarian cancer diagnostics. Based on the above, a model able to identify ovarian cancer and improve the accuracy of correct diagnosis and disease severity will be proposed.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record
Print a page for my doctorData and sources
- Registry record
- Listed on the EU's official list of trials (CTIS).
- Official title
- IMPROCAS - Improved Prediction of Ovarian Cancer Surgery
- Plain-language title
- Testing blood tests and MRI scans to better detect ovarian cancerGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 9 November 2026.
- Record updated
- 30 May 2025