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Not yet taking people in GermanyPhase 1

Skepinone-L added to sorafenib for advanced liver cancer not caused by viruses

Tests Skepinone-L with sorafenib in adults with advanced hepatocellular carcinoma.

Key facts

Who runs it
Universitaetsklinikum Tuebingen AöR
Where
Tuebingen, GermanySee the site
Registry title
A phase I, open-label, dose-escalation, safety, pharmacokinetic/-dynamic and clinical activity study of p38α inhibitor Skepinone-L to enhance therapeutic efficacy of Sorafenib in advanced hepatocellular carcinomas of non-viral origin
Status
Not yet recruiting
Phase
Phase 1
People taking part
20 people, planned
Starts
1 Dec 2026
Expected to end
31 Jul 2032
Type of study
Interventional
Record updated
29 September 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with advanced hepatocellular carcinoma (a liver cancer) that was not caused by a virus. It tests Skepinone-L together with Sorafenib.

Age
18 years or older
Sex
All sexes can join
Disease stage
Advanced hepatocellular carcinoma of non-viral origin

Where in Germany

  • Universitaetsklinikum Tuebingen AöRTuebingen, GermanyNot yet recruiting

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record

Print a page for my doctor

Data and sources

Registry record
Listed on the EU's official list of trials (CTIS).
Plain-language title
Skepinone-L added to sorafenib for advanced liver cancer not caused by virusesGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 9 November 2026.
Record updated
29 September 2026