Using abdominal pressure and ultrasound to guide fluid removal in acute heart failure
Tests whether abdominal pressure and ultrasound guide water-removing treatment in adults with acute heart failure.
Plain-language title generated from the registry record
Registry title: The role of intra-abdominal pressure and point of care ultrasound to guide decongestive therapy in Heart Failure (ABDOPOCUS-HF)
Key facts
- Where
- A Coruna, Avilés (Asturias), Girona, Lleida, Madrid, Majadahonda, Málaga, Murcia, San Sebastián de los Reyes, Sevilla, Tudela, Valencia, and Zaragoza, SpainSee the 15 sites
- Phase
- Phase 3
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults in hospital with acute heart failure and signs of fluid build-up. It tests whether pressure in the belly and ultrasound can guide water-pill treatment.
- Age
- Over 18 years
- Sex
- Men and women
- Disease stage
- Acute heart failure with at least one clinical sign of congestion: swelling (edema), fluid in the belly (ascites) or fluid around the lungs (pleural effusion).
- Earlier treatment
- Not stated. Staying more than 24 hours in the internal medicine department before joining is not allowed.
- Biomarker or test result
- NT-proBNP above 1000 pg/mL or BNP above 250 pg/mL.
Main reasons for not taking part
- Systolic blood pressure below 100 mmHg at admission
- Cardiogenic shock or acute heart muscle ischemia
- Kidney replacement therapy, such as ultrafiltration or peritoneal dialysis
- Kidney transplant, recent heart surgery (last year) or heart transplant
- Pregnancy or breastfeeding
Read by machine on 9 November 2026.
Where in Spain
- Complejo Hospitalario Universitario Juan CanalejoA Coruna, SpainTaking people
- Hospital San Agustín de AvilésAvilés (Asturias), SpainTaking people
- Hospital Universitari de Girona Doctor Josep TruetaGirona, SpainTaking people
- Hospital Universitari Arnau De Vilanova De La Gerencia Territorial De LleidaLleida, SpainTaking people
- Hospital Clínico San CarlosMadrid, SpainTaking people
- Hospital Universitario Infanta LeonorMadrid, SpainTaking people
- Hospital Universitario Ramón y CajalMadrid, SpainTaking people
- Hospital Universitario Puerta de Hierro de MajadahondaMajadahonda, SpainTaking people
- Hospital Universitario Virgen de la VictoriaMálaga, SpainTaking people
- University Clinical Hospital Virgen De La ArrixacaMurcia, SpainTaking people
- Hospital Universitario Infanta SofiaSan Sebastián de los Reyes, SpainTaking people
- Hospital Universitario Virgen De La MacarenaSevilla, SpainTaking people
- Hospital Reina SofíaTudela, SpainTaking people
- Consorcio Hospital General Universitario de ValenciaValencia, SpainTaking people
- Hospital Clinico Universitario Lozano BlesaZaragoza, SpainTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record
Print a page for my doctorTrial details
- Who runs it
- Fundacion Instituto De Investigacion Sanitaria Aragon
- Trial code
- EU 2024-512901-22-00
- Record updated
- 25 May 2026
- Original description
To evaluate the complete resolution of congestion (ADVOR scale) after the first 72 hours of intravenous diuretic treatment on the hospital ward, between the standard treatment group and the intervention group (intra-abdominal pressure and ultrasound)Read full original descriptionShow less
Utility of intra-abdominal pressure and clinical ultrasound for guiding diuretic treatment in patients with acute heart failure
To evaluate the complete resolution of congestion (ADVOR scale) after the first 72 hours of intravenous diuretic treatment on the hospital ward, between the standard treatment group and the intervention group (intra-abdominal pressure and ultrasound)
Inclusion: Men or women over 18 years of age; Diagnosis of HF based on the latest HF guidelines published in 2022; NT-proBNP > 1000 pg/mL or BNP > 250 pg/mL; Bladder catheterization in order to perform intra-abdominal pressure measurement; Intravascular or mixed pattern of congestion, defined as the presence of one or more clinical signs of congestion (edema, ascites and/or pleural effusion); Signature of the informed consent.
Exclusion: Patients receiving renal replacement therapy (ultrafiltration or peritoneal dialysis); Renal transplant recipients; Previous history of hypersensitivity to hydrochlorothiazide or furosemide; Heart rate at admission > 170 beats per minute (bpm); Acute myocardial ischemia; Patients with recent cardiac surgery (last year) or cardiac transplant recipients; Need for inotropic support to maintain adequate cardiac and/or renal output; Serum hemoglobin < 9 g/dL; Patient with stay in the internal medicine department > 24 hours; Systolic blood pressure at admission < 100 mmHg; Cardiogenic shock; Patients whose origin is the Intensive Care Unit; Pregnancy or lactation; Absence of sufficient clinical congestion (ADVOR score = 0 at the time of randomization); Patient refusal to participate in the clinical trial; Inability or contraindication to bladder catheterization.