Not yet taking people in BelgiumPhase 4
Testing acetazolamide with an SGLT2 inhibitor for fluid overload in heart failure
Tests acetazolamide with an SGLT2 inhibitor in adults with acute heart failure and fluid overload.
Key facts
- Who runs it
- Ziekenhuis Oost Limburg
- Where
- Genk, BelgiumSee the site
- Registry title
- Acetazolamide in combination with SGLT2i in patients with volume overload and acute heart failure
- Status
- Not yet recruiting
- Phase
- Phase 4
- People taking part
- 30 people, planned
- Started
- 22 Jan 2024
- Planned end
- 31 Dec 2025
- Type of study
- Interventional
- Record updated
- 15 January 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with heart failure who are holding too much fluid and need an added SGLT2i and IV loop diuretic treatment.
- Age
- 18 years or older
- Sex
- All sexes can join.
- Disease stage
- Heart failure with fluid overload, judged by the treating cardiologist to need an added SGLT2i and IV loop diuretic therapy.
- Earlier treatment
- Must already take loop diuretics long-term, at least 40mg of furosemide or equivalent.
Main reasons for not taking part
- Kidney function with an eGFR below 20ml/min/1.73m² (result within the last 6 months)
- Cannot collect 24h urine
- Systolic blood pressure below 90mmHg
The registry criteria, word for word
Show all 7 criteriaShow less
Who can take part
- 18 years or older
- Heart Failure
- Maintenance therapy with loop diuretics of at least 40mg of furosemide or equivalents
- Deemed volume overloaded by treating cardiologist warranting the addition of SGLT2i and IV loop diuretic therapy
Who cannot take part
- Kidney function impairment with an eGFR <20ml/min/1.73m² (result within last 6 months)
- Inability to collect 24h urine collections
- Systolic blood pressure below 90mmHg
Where in Belgium
- Ziekenhuis Oost-LimburgGenk, BelgiumNot yet recruiting
About the trial
What the trial wants to find out
Improvement in natriuresis
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record
Print a page for my doctorData and sources
- Registry record
- Listed on the EU's official list of trials (CTIS).
- Official title
- Acetazolamide in combination with SGLT2i in patients with volume overload and acute heart failure
- Plain-language title
- Testing acetazolamide with an SGLT2 inhibitor for fluid overload in heart failureGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 9 November 2026.
- Record updated
- 15 January 2025