Frontlight ResearchEarly access
Not yet taking people in FinlandPhase 4
Compares laser treatment with eye drops for exfoliation glaucoma
Tests laser treatment against eye drops as first treatment in adults with exfoliation glaucoma.
Key facts
- Who runs it
- HUS-Yhtymae
- Where
- Helsinki, FinlandSee the site
- Registry title
- Selective laser trabeculoplasty versus eye drops for first line treatment of exfoliation ocular hypertension or glaucoma: a randomised clinical trial
- Status
- Not yet recruiting
- Phase
- Phase 4
- People taking part
- 112 people, planned
- Started
- 3 Nov 2020
- Expected to end
- 1 Dec 2030
- Type of study
- Interventional
- Record updated
- 19 December 2024
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for people aged 50 to 100 with newly found exfoliation glaucoma or raised eye pressure. It compares laser treatment with eye drops as the first treatment.
- Age
- 50 to 100 years
- Sex
- Men and women can join.
- Disease stage
- Newly diagnosed exfoliation glaucoma, or raised eye pressure (ocular hypertension) of 24 mmHg or more, with eye pressure below 35 mmHg.
- Earlier treatment
- No previous eye operation inside the eye, except an uncomplicated cataract operation 1 year ago or earlier.
Main reasons for not taking part
- Advanced glaucoma
- Starting eye pressure of 35 mmHg or more
- Visual acuity of 0.2 or worse
- Angle closure, significant cataract or other active eye disease
- Unable to use eye drops
The registry criteria, word for word
Show all 17 criteriaShow less
Who can take part
- Informed consent
- Age of 50 –100 years
- Possibility to attend 12 months of period
- Exfoliation
- Newly diagnosed exfoliation glaucoma by EGS (European glaucoma society) guidelines or ocular hypertensio TA 24 mmHg or more
- Eye pressure less than 35 mmHg
Who cannot take part
- Previous intraocular operation excluding uncomplicated cataracta surgery 1 year ago or earlier
- Serious other medical condition preventing participation in the trial
- Other active eye disease (active uveitis, clinical significant macular edema, wet AMD, proliferative diabetic retinopathy, intraocular tumor, intraocular injections, IOL luxation)
- Advanced glaucoma
- Participating in other clinical trial
- Target IOP less than 15
- Starting eye pressure 35 or more
- Visual acuity 0.2 or worse
- Angle closure
- Unable to use eye drops
- Significant cataract
Where in Finland
- HUS-YhtymaeHelsinki, FinlandNot yet recruiting
About the trial
What the trial wants to find out
The main objective of the trial is to show the equilance in efficacy of SLT laser treatment compared to medical therapy as a primary therapy in exfoliation glaucoma.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record
Print a page for my doctorData and sources
- Registry record
- Listed on the EU's official list of trials (CTIS).
- Official title
- Selective laser trabeculoplasty versus eye drops for first line treatment of exfoliation ocular hypertension or glaucoma: a randomised clinical trial
- Plain-language title
- Compares laser treatment with eye drops for exfoliation glaucomaGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 9 November 2026.
- Record updated
- 19 December 2024