Frontlight ResearchEarly access
Taking people in SpainPhase 1
Tests JNJ-95437446 in people with advanced solid tumors that returned or worsened
Tests JNJ-95437446 in adults with advanced lung, colorectal or head and neck cancer.
Key facts
- Who runs it
- Janssen Cilag International
- Where
- Barcelona and Madrid, SpainSee the 4 sites
- Trial code
- Registry title
- A Phase 1 study of JNJ-95437446 in participants with advanced-stage solid tumors
- Status
- Recruiting
- Phase
- Phase 1
- People taking part
- 52 people, planned
- Started
- 3 Nov 2025
- Expected to end
- 18 Nov 2027
- Type of study
- Interventional
- Record updated
- 8 June 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with advanced non-small cell lung cancer, colorectal cancer or head and neck squamous cell cancer that came back or grew after standard treatment.
- Age
- 18 years or older
- Sex
- Men and women
- Disease stage
- Locally advanced or metastatic NSCLC, CRC or HNSCC that has recurred or progressed after prior standard of care therapy
- Earlier treatment
- Must have had standard of care therapy before, and the cancer came back or grew
Where in Spain
- Hospital Universitari Vall d'HebronBarcelona, SpainTaking people
- Hospital Universitario 12 de OctubreMadrid, SpainTaking people
- Hospital Universitario Fundación Jiménez DíazMadrid, SpainTaking people
- Hospital Universitario HM SanchinarroMadrid, SpainTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record
Print a page for my doctorData and sources
- Registry record
- Listed on the EU's official list of trials (CTIS).
- Plain-language title
- Tests JNJ-95437446 in people with advanced solid tumors that returned or worsenedGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 9 November 2026.
- Record updated
- 8 June 2026