Taking people in NorwayPhase 2
Two moisturising creams to keep atopic dermatitis from coming back
Tests two moisturising creams against no treatment in adults with atopic dermatitis.
Key facts
- Who runs it
- Galenica AB
- Where
- Oslo, NorwaySee the siteAlso in 1 other country, 10 sites
- Trial code
- Registry title
- Efficacy and safety of two moisturising creams for maintenance treatment of atopic dermatitis
- Status
- Recruiting
- Phase
- Phase 2
- People taking part
- 78 people, planned
- Started
- 26 Jan 2026
- Expected to end
- 31 Dec 2027
- Type of study
- Interventional
- Record updated
- 28 October 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with moderate to severe atopic dermatitis who have eczema patches on both arms and/or legs. It tests two moisturising creams against no treatment.
- Age
- 18 years or older
- Sex
- All sexes can join
- Disease stage
- Moderate to severe atopic dermatitis (IGA 3 or higher, mEASI score of 4 or higher on the study areas). Two eczema patches of 2 x 2 cm (0.8 in) to 10 x 10 cm (3.9 in), one on each side of the body, with similar size. The investigator must expect the patches to clear completely with about 4 weeks of class III corticosteroid treatment.
- Earlier treatment
- No systemic drugs, class IV topical corticosteroids or light treatment for atopic dermatitis in the last 3 months.
Main reasons for not taking part
- Eczema only on the hands
- Mild atopic dermatitis
- Known allergy or sensitivity to any of the study products
- Pregnant, breastfeeding or planning to become pregnant during the study
- Poor compliance or difficulty reading and understanding the local language, as judged by the investigator
The registry criteria, word for word
Show all 13 criteriaShow less
Who can take part
- The patient has given their written consent to participate in the study
- Age ≥ 18 years
- Patients with known AD or diagnosed with AD according to the Williams criteria [1] with visible atopic lesions on arms and/or legs. Two lesions on left respective right side with a size of 2 x 2 cm to 10 x 10 cm should be available, i.e., study areas. The largest lesion should not be more than 50% larger than the smallest lesion in length and width, i.e., the length of the largest selected lesion ≤ 1.5× the length of the smallest and the width of the largest selected lesion ≤ 1.5× width of the smallest lesion
- Moderate to severe form of AD, IGA ≥ 3 [2], a mEASI score on the defined study areas of ≥ 4 and with a difference between left study area to right study area of ≤ 1 and which, in the opinion of the Investigator, can achieve complete clearance with a class III corticosteroid treatment for approximately 4 weeks
Who cannot take part
- Patients treated for AD with systemic drugs, topical corticosteroids class IV and light treatment during the last 3 months
- Any concomitant medications that, in the opinion of the Investigator, could affect the study outcome
- Known sensitivity or allergy to any of the study products
- Any condition for which, in the opinion of the Investigator, participation would not be in the best interest of the participant (e.g., compromise well-being) or that could prevent, limit, or confound the protocol-specified assessments or procedures
- Eczema exclusively on the hands
- Patients assessed by the Investigator to have mild atopic dermatitis
- Patients assessed by the Investigator to have poor compliance
- Patients assessed by the Investigator to have difficulty reading and understanding the local language
- Patients who are pregnant, breast feeding or planning to become pregnant during study participation
Where in Norway
Also in 1 other country, 10 sites
- Hudklinikken ASOslo, NorwayTaking people
About the trial
What the trial wants to find out
To demonstrate superiority in time to relapse of eczema with moisturisers Oviderm cream and Urea/propylene glycol cream, respectively, as compared to non-treatment
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record
Print a page for my doctorData and sources
- Registry record
- Listed on the EU's official list of trials (CTIS).
- Official title
- Efficacy and safety of two moisturising creams for maintenance treatment of atopic dermatitis compared to no treatment: A prospective, controlled, split-body study
- Plain-language title
- Two moisturising creams to keep atopic dermatitis from coming backGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 9 November 2026.
- Record updated
- 28 October 2026