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Taking people in GermanyPhase 1

Tests EGL-003 safety in healthy volunteers and adults with atopic dermatitis

Tests a new drug, EGL-003, for safety and dosing in adults with atopic dermatitis.

Key facts

Who runs it
Egle Therapeutics
Where
Bad Bentheim, Berlin, Dresden, and Mainz, GermanySee the 4 sitesAlso in 2 other countries, 14 sites
Registry title
A first-in-human, dose finding study to evaluate the safety, tolerability and pharmacokinetics of EGL-003 in healthy volunteers followed by adults with autoimmune disease.
Status
Recruiting
Phase
Phase 1
People taking part
80 people, planned
Started
27 Oct 2025
Expected to end
30 Nov 2028
Type of study
Interventional
Record updated
28 August 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for healthy adult volunteers first, then adults with an autoimmune disease. It tests the safety and dose of EGL-003.

Age
18 to 64 years
Sex
All sexes can join.

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 64 years old?

Where in Germany

Also in 2 other countries, 14 sites

  • Thermalsole und Schwefelbad Bentheim GmbHBad Bentheim, GermanyTaking people
  • Charite Universitaetsmedizin Berlin KöRBerlin, GermanyTaking people
  • Universitaetsklinikum Carl Gustav Carus Dresden an der Technischen Universitaet Dresden AöRDresden, GermanyTaking people
  • Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöRMainz, GermanyTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record

Print a page for my doctor

Data and sources

Registry record
Listed on the EU's official list of trials (CTIS).
Plain-language title
Tests EGL-003 safety in healthy volunteers and adults with atopic dermatitisGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 9 November 2026.
Fit questions
Built from 2025-521658-40-00, who can take part
Record updated
28 August 2026