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Taking peoplePhase 1

Tests a radioactive drug and a scan agent in adults with advanced solid tumors

Tests a radioactive drug and a scan agent in adults with advanced cancers.

Key facts

Who runs it
Novartis Pharma AG
Where
Barcelona and L'Hospitalet de Llobregat, SpainSee the 2 sitesAlso in 4 other countries, 8 sites
Trial code
Registry title
A phase I open-label, multi-center study to evaluate the safety, tolerability, dosimetry, and preliminary activity of [177Lu]Lu-DFC413 and safety and imaging properties of [68Ga]Ga-NNS309 in patients with solid tumors
Status
Recruiting
Phase
Phase 1
People taking part
62 people, planned
Started
21 May 2026
Expected to end
16 Mar 2029
Type of study
Interventional
Record updated
15 September 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with advanced solid tumours that cannot be removed by surgery or have spread. It tests the safety and early activity of [177Lu]Lu-DFC413 and the imaging agent [68Ga]Ga-NNS309.

Age
18 years or older
Sex
All sexes can join.
Disease stage
Locally advanced and unresectable, or metastatic. Cancer types: soft tissue sarcoma (not GIST or Kaposi sarcoma), pancreatic ductal adenocarcinoma, non-small cell lung cancer, colorectal cancer, triple negative breast cancer, or HR+/HER2- ductal or lobular breast cancer.

Main reasons for not taking part

  • Healthy volunteers cannot join.
  • People with GIST or Kaposi sarcoma cannot join.

Where in Spain

Also in 4 other countries, 8 sites

  • Hospital Universitari Vall d'HebronBarcelona, SpainNot yet recruiting
  • Institut Catala D'oncologiaL'Hospitalet de Llobregat, SpainNot yet recruiting

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record

Print a page for my doctor

Data and sources

Registry record
Listed on the EU's official list of trials (CTIS).
Plain-language title
Tests a radioactive drug and a scan agent in adults with advanced solid tumorsGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 9 November 2026.
Record updated
15 September 2026