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Taking people in NetherlandsPhase 1/2

Using a PET scan to look for microclots in long COVID

Tests whether PET scans can show microclots in adults with long COVID.

Key facts

Who runs it
Amsterdam UMC Stichting
Where
Amsterdam, NetherlandsSee the site
Registry title
Locating microclots with PET in post-COVID syndrome
Status
Recruiting
Phase
Phase 1/2
People taking part
65 people, planned
Started
5 Jul 2026
Expected to end
31 Dec 2026
Type of study
Interventional
Record updated
7 May 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults who had COVID-19 at least 12 months ago, to compare microclots on a PET scan. Post-COVID patients and controls are compared.

Age
40-65 years (the registry lists 18 to 64 years)
Sex
All sexes
Disease stage
Symptomatic COVID-19 confirmed by a positive PCR test for SARS-CoV-2, at least 12 months ago.
Earlier treatment
Must not use anti-coagulant drugs.
Biomarker or test result
Positive PCR test for SARS-CoV-2 when COVID-19 was diagnosed.

Main reasons for not taking part

  • Other conditions linked to amyloid formation, such as diabetes, rheumatoid arthritis or neurodegenerative disorders
  • Cannot undergo scanning, for example due to claustrophobia, severe back pain or fear of needles
  • Uses anti-coagulant drugs
  • Women who can have children and are not surgically sterile, not abstaining from sex or not using reliable contraception

The registry criteria, word for word

Show all 9 criteriaShow less

Who can take part

  • The subject was diagnosed with symptomatic COVID-19, confirmed by a positive PCR for SARS-CoV-2
  • The subject is at least 12 months after being diagnosed with COVID-19
  • The subject is in the range 40-65 years of age (to ensure radiation safety)
  • The subject has sufficient command of the Dutch language
  • The subject is able to undergo the (PET) scanning procedures

Who cannot take part

  • The subject is using anti-coagulant drugs
  • The subject has other medical conditions linked to amyloid-formation, such as diabetes, rheumatoid arthritis or neurodegenerative disorders
  • The subject is unable to undergo scanning procedures due to for example claustrophobia, severe back pain or trypanophobia (fear of needles)
  • The subject is a female of childbearing potential who is not surgically sterile, not refraining from sexual activity or not using reliable methods of contraception

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 64 years old?

Where in Netherlands

  • Amsterdam UMC StichtingAmsterdam, NetherlandsTaking people

About the trial

What the trial wants to find out

To assess whether we are able to visualize and quantify a difference in amyloid containing microclots between post-COVID patients and controls using total-body dynamic [18F]flutemetamol PET.

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record

Print a page for my doctor

Data and sources

Registry record
Listed on the EU's official list of trials (CTIS).
Official title
LAMP-COVID: Locating Amyloid-containing Microclots with total-body PET in post-COVID syndrome
Plain-language title
Using a PET scan to look for microclots in long COVIDGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 9 November 2026.
Fit questions
Built from 2025-522348-42-00, who can take part
Record updated
7 May 2026