Comparing two bowel cleansing solutions before colonoscopy to screen for colorectal cancer

Who can take part

• Men and women aged 49 to 70
• Have participated in the early detection program for colorectal cancer
• Positive result in the fecal occult blood test (≥20 μg Hb/g feces)
• Scheduled screening colonoscopy at Hospital Clínic de Barcelona
• Signed informed consent form

Who cannot take part

• Partial or total colon resection
• Severe renal failure (grade IV or V) (Annex 5, Stages of Renal Impairment) and/or congestive heart failure (New York Heart Association Scale Class III and IV) (Annex 6, NYHA Scale)
• Hypersensitivity to the active ingredients of excipients
• Mental disability or severe mental disorder (schizophrenia and other psychotic disorders, recurrent severe major depressive disorders, severe obsessive-compulsive disorder, severe personality disorders, and bipolar disorders)
• Personal history of CRC or colorectal pathology that requires specific follow-up (ulcerative colitis, Crohn's disease)
• Terminal illness or serious illness/disability that contraindicates subsequent colon study
• Gastrointestinal disorders that contraindicate the use of study products (gastric emptying disorders, gastrointestinal perforation or obstruction, ileus, toxic megacolon)
• Glucose-6-phosphate dehydrogenase deficiency
• Hypermagnesemia
• Rhabdomyolysis
• Phenylketonuria
• Pregnancy or breastfeeding
• Colonoscopy within the last year
• Barthel Index of <20 (Annex 4, Barthel Index) and who also meet the Rome IV Criteria for the diagnosis of functional constipation (Annex 7, Rome IV Criteria)
• Do not understand spoken or written Catalan or Spanish