18F-FAPI-74 PET/CT scans to detect cancer spread in non-small cell lung cancer
Tests 18F-FAPI-74 scans for finding cancer spread in adults with non-small cell lung cancer.
Key facts
- Who runs it
- Turku University Hospital
- Where
- Turku, FinlandSee the site
- Trial code
- Registry title
- The Expression of Fibroblast Activation Protein in Patients with Non-Small Cell Lung Cancer Patients
- Status
- Not yet recruiting
- Phase
- Phase 2
- People taking part
- 60 people, planned
- Started
- 1 Oct 2025
- Expected to end
- 31 Dec 2028
- Type of study
- Interventional
- Record updated
- 16 December 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with non-small cell lung cancer (adenocarcinoma or squamous cell carcinoma). It tests a PET/CT scan with 18F-FAPI-74 to look for cancer spread.
- Age
- 18 to 64 years
- Sex
- All sexes can join.
- Disease stage
- Adenocarcinoma or squamous cell lung cancer confirmed by tissue tests. Study 1: stage I-III.
- Earlier treatment
- Study 1: no earlier treatment (surgery, radiotherapy or medicine) for this lung cancer. Study 2: earlier lobectomy, stereotactic radiotherapy or chemoradiotherapy.
Main reasons for not taking part
- Uncontrolled serious infection
- Another cancer
- Known sarcoidosis
- Study 2: less than six months after radiotherapy
- Cannot understand the purpose of the study, or a medical condition that rules out a whole-body PET-CT
The registry criteria, word for word
Show all 2 criteriaShow less
Who can take part
- Diagnosis: Histologically confirmed adenocarcinoma or squamous cell carcinoma. Study 1: No previous treatment (surgical, radiotherapy or medical treatment) for NSCLC. Study 2: Lobectomy or stereotactical radiotherapy or chemoradiotherapy for NSCLC. Clinical stage: Study 1: Stage I-III, Age: > 18 yo
Who cannot take part
- Infections: Patient must not have an uncontrolled serious infection - no other malignancies - no known history of sarcoidosis - Study 2: under six months after radiotherapy - Patient is not able to understand purpose of study - Medical conditions prohibiting whole body PET-CT
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 64 years old?
Where in Finland
- Turku University HospitalTurku, FinlandNot yet recruiting
About the trial
What the trial wants to find out
1) To explore the feasibility of 18F-FAPI-74 PET/CT imaging in the clinical assessment of patients with lymph node metastases in NSCLC 2) To explore the feasibility of 18F-FAPI-74 PET/CT imaging in the assessment of cancer related distant metastasis in patient level in patients with primary NSCLC 3) To explore the feasibility of 18F-FAPI-74 PET/CT imaging in the assessesment of cancer related local lymph metastasis and distant metastasis in patient level in patients with recurrent NSCL.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record
Print a page for my doctorData and sources
- Registry record
- Listed on the EU's official list of trials (CTIS).
- Official title
- The Expression of Fibroblast Activation Protein in Patients with Non-Small Cell Lung Cancer Patients
- Plain-language title
- 18F-FAPI-74 PET/CT scans to detect cancer spread in non-small cell lung cancerGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 9 November 2026.
- Fit questions
- Built from 2025-523965-97-00, who can take part
- Record updated
- 16 December 2025