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Long-term study following people with fatty liver disease

Studies liver tissue samples from people with fatty liver disease and NASH over time.

Plain-language title generated from the registry record
Registry title: Prospective Cohort Study in Patients With NAFLD

Key facts

Where
Zurich, SwitzerlandSee the site

Where in Switzerland

  • University Hospital Zurich, Endocrinology and DiabetologyZurich, SwitzerlandTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
University of Zurich
Trial code
NCT00575133
Record updated
24 February 2012
Original description
To assess the importance of intracellular signalling pathways and its deregulation in adiposity and diabetes-related insulin resistance, liver tissue samples of patients suffering from non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH)will be analyzed prospectively from a liver tissue bank.Read full original descriptionShow less

Multicentric, Prospective, Non-interventional, Long-term Cohort Study in Patients With Non-alcoholic Fatty Liver Disease (NAFLD)

To assess the importance of intracellular signalling pathways and its deregulation in adiposity and diabetes-related insulin resistance, liver tissue samples of patients suffering from non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH)will be analyzed prospectively from a liver tissue bank.

Inclusion: Patients with histologically confirmed fatty liver disease.

Exclusion: Hepatotoxic medication (e.g. amiodarone); History of significant alcohol consumption; Viral hepatitis; Autoimmune hepatitis; Metabolic diseases (e.g. hemochromatosis, M. Wilson, alpha 1-antitrypsin deficiency).

ClinicalTrials.gov NCT00575133