Tests an implanted stimulator to help paralyzed people move their legs
Tests an implanted electrical device to help people with paralysis exercise, stand and step.
Plain-language title generated from the registry record
Registry title: Evaluation of an Advanced Lower Extremity Neuroprostheses
Key facts
- Where
- Cleveland, United StatesSee the 2 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 21 and 75 years old?
Source: NCT00623389, who can take part
Where in United States
- Louis Stokes Cleveland VA Medical CenterCleveland, United StatesTaking people
- MetroHealth SystemCleveland, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Case Western Reserve University
- Trial code
- NCT00623389
- Record updated
- 10 July 2026
- Original description
The purpose of this study is to evaluate a surgically implanted functional electrical stimulation (FES) system to facilitate exercise, standing, stepping and/or balance in people with various degrees of paralysis.Read full original descriptionShow less
Evaluation of Advanced Lower Extremity Neuroprostheses
The purpose of this study is to evaluate a surgically implanted functional electrical stimulation (FES) system to facilitate exercise, standing, stepping and/or balance in people with various degrees of paralysis.
Phase I Inclusion Criteria; Skeletal maturity and ability to sign informed consent (>18 years); Non-ventilator dependent paralysis resulting from injuries such as: mid cervical/thoracic (C4 or below) spinal cord injuries, poststroke hemiparesis, TBI, or MS, affecting the trunk and/or lower limbs; Innervated and excitable lower extremity and trunk musculature; Adequate social support and stability; Willingness to comply with follow-up procedures; Phase I Exclusion Criteria; Non-English speaking; Females who are pregnant; Current pressure injuries that would be exacerbated by study activities; Severe contractures or uncontrolled spasticity of any major joint of the upper or lower extremities that results in a fixed deformity that would interfere with study activities; History of spontaneous fractures or other evidence of excessively low bone density; History of vestibular dysfunction, balance problems, or spontaneous falls; Acute and or/untreated orthopedic problems that would prevent a participant from weight bearing or exercising such as a dislocation or fracture.