Blood Proteins Measured During Heart Attacks and Later Heart Failure
Measures two blood proteins in adults having a heart attack.
Plain-language title generated from the registry record
Registry title: Circulating Markers for Ischemic Heart Disease
Key facts
- Where
- Farmington, United StatesSee the site
Where in United States
- University of Connecticut Health CenterFarmington, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- UConn Health
- Trial code
- NCT00762333
- Record updated
- 17 August 2026
- Original description
The purpose of this research is to determine if two proteins in the blood are increased during acute myocardial infarction and whether their levels are higher in those who develop heart failure than those who do not. These two proteins are produced and potentially released when the heart muscle is damaged. They may then be released into the blood and be detected by standard method in the research laboratory. At this time, detection of an increase in these proteins in the blood is not known to be associated with any disease or myocardial infarction.Read full original descriptionShow less
Circulating Markers for Ischemic Heart Disease
The purpose of this research is to determine if two proteins in the blood are increased during acute myocardial infarction and whether their levels are higher in those who develop heart failure than those who do not. These two proteins are produced and potentially released when the heart muscle is damaged. They may then be released into the blood and be detected by standard method in the research laboratory. At this time, detection of an increase in these proteins in the blood is not known to be associated with any disease or myocardial infarction.
Inclusion: men and women, 18 years of age and over with acute myocardial infarction (determined by positive cardiac markers -CKMB/ troponin) with or without heart failure (dyspnea, rales, edema, elevated jugular venous pressure, ascites); Heart failure can be diagnosed using imaging evidence such as dilated heart, poor contractile function or echocardiographic Doppler evidence of diastolic dysfunction or elevated right- or left-sided filling pressures; A control group of male subjects age 60 and older without history of MI or heart disease.
Exclusion: Subjects who have undergone cardiac or non-cardiac surgery in the 3 months prior to enrollment; Subjects unable to give consent.