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Enrolling by invitationPhase 4

Brain Imaging of Amyloid Plaques in Aging and Memory Disorders

Uses PET brain scans with a tracer to track amyloid plaques over time.

Plain-language title generated from the registry record
Registry title: Imaging of Brain Amyloid Plaques in the Aging Population

Key facts

Where
Rochester, United StatesSee the site
Phase
Phase 4

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 30 and 100 years old?

Source: NCT00950430, who can take part

Where in United States

  • Mayo ClinicRochester, United StatesNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Mayo Clinic
Trial code
NCT00950430
Record updated
23 June 2026
Original description
This is a prospective, open label, non-therapeutic, diagnostic imaging study. The purpose of this study is to utilize Pittsburgh Compound B positron emission imaging (PiB PET) to ascertain the relationship between change in amyloid burden over time, and concurrent change in clinical status.Read full original descriptionShow less

Brain Amyloid Imaging With Pittsburgh Compound B in Normal Aging, Mild Cognitive Impairment, and Dementia

This is a prospective, open label, non-therapeutic, diagnostic imaging study. The purpose of this study is to utilize Pittsburgh Compound B positron emission imaging (PiB PET) to ascertain the relationship between change in amyloid burden over time, and concurrent change in clinical status.

Inclusion: Age 30-100; Subjects who have completed or are scheduled to undergo the neurological evaluation procedures in the Mayo Clinic Study of Aging, Mayo ADRC, or Mayo neurodegenerative disease clinics.

Exclusion: Subjects unable to lie down without moving for 10 minutes; Women who are pregnant or cannot stop breast feeding for 24 hours at the time of scanning; Claustrophobic patients unable to tolerate the scans; Standard safety exclusionary criteria for MRI such as metallic foreign bodies, pacemaker, etc.

ClinicalTrials.gov NCT00950430