Studying Heart Tissue and Blood Samples From Patients With Advanced Heart Failure
Collects heart tissue and blood samples from people with end-stage heart failure for research.
Plain-language title generated from the registry record
Registry title: Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease
Key facts
- Where
- Murray and Salt Lake City, United StatesSee the 3 sites
Where in United States
- Intermountain Medical CenterMurray, United StatesTaking people
- University of Utah Health Sciences CenterSalt Lake City, United StatesTaking people
- VA Salt Lake City Health Care SystemSalt Lake City, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Utah
- Trial code
- NCT01099982
- Record updated
- 13 August 2026
- Original description
Hypothesis:Read full original descriptionShow less
Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease, Effects of Mechanical Unloading on Myocardial Function and Structure in Humans
Hypothesis:
Tissue and serum samples collected from end-stage heart failure patients receiving left ventricular assist device implantation (LVAD) or heart transplantation will provide information regarding the basic science of heart disease. Tissue and serum samples collected from a limited numbers of "healthy controls" (donor grafts that were not utilized for heart transplantation) will serve as a comparator in research database projects.
Design:
This is a registry project; there are no investigational treatments, drug or procedures associated with participation in registry activities. This project is an organized functional data and tissue data gathering and storing (database) endeavor with specific focus on the functional, structural, and molecular aspects of heart failure. Data collection will not immediately influence the course of treatment for any patient.
Inclusion: >18 years of age diagnosed with heart failure undergoing either LVAD implantation or heart transplantation; 13 to 18 years of age, specifically, older children with heart failure whose body mass index is large enough to accommodate and LVAD.
Exclusion: Neither patient nor patient representative understands spoken English; Neither patient nor patient's personal representative is willing to give written consent for participation.