Development of Charcot Marie Tooth Disease (CMT) Pediatric Scale for Children With CMT
Key facts
- Where
- Ann Arbor, Chapel Hill, Hartford, Iowa City, Orlando, Palo Alto, Philadelphia, Rochester, and Seattle, United StatesSee the 9 sites
Where in United States
- University of MichiganAnn Arbor, United StatesNo longer taking part
- University of North CarolinaChapel Hill, United StatesNo longer taking part
- University of Connecticut/Connecticut Children's Medical CenterHartford, United StatesNo longer taking part
- University of IowaIowa City, United StatesNo longer taking part
- Nemours Children's ClinicOrlando, United StatesNo longer taking part
- Stanford UniversityPalo Alto, United StatesNo longer taking part
- Children's Hospital of PhiladelphiaPhiladelphia, United StatesNo longer taking part
- University of RochesterRochester, United StatesNo longer taking part
- Seattle Children's HospitalSeattle, United StatesNo longer taking part
Trial details
- Who runs it
- University of Iowa
- Trial code
- NCT01203085
- Record updated
- 27 October 2026
- Original description
The primary goal of this project is to develop and test a Charcot Marie Tooth disease (CMT) Pediatric Scale for use in evaluation in natural history CMT study.Read full original descriptionShow less
Development and Validation of CMT Pediatric Scale for Children With Charcot Marie Tooth
The primary goal of this project is to develop and test a Charcot Marie Tooth disease (CMT) Pediatric Scale for use in evaluation in natural history CMT study.
Inclusion: All patients MUST be seen in person at one of the participating centers for enrollment in this study; Children (< 21 years of age); Known or probable inherited neuropathies classified as CMT1, CMT2, or CMT4.
Exclusion: Known diagnoses of acquired neuropathy including toxic (e. g. medication related neuropathies); metabolic (e.g. diabetic), immune mediated or inflammatory [acute inflammatory demyelinating polyradiculoneuropathy (AIDP) or chronic inflammatory demyelinating polyneuropathy (CIDP)] polyneuropathies; neuropathy related to leukodystrophy, congenital muscular dystrophy; and patients with severe general medical conditions; Entirely normal conduction velocities of upper and lower limbs as this suggests that the subject may not have a neuropathy.