Pelvic and Aortic-cava Lymphadenectomy Randomized for Ovarian Cancer
Reason given: qualitative analysis of the study database
Key facts
- Where
- Amiens, Angers, Brest, Clermont-Ferrand, Dijon, Lyon, Marseille, Montpellier, Paris, Rennes, Saint-Cloud, Saint-Herblain, Strasbourg, Toulouse, and Tours, FranceSee the 19 sites
- Phase
- Phase 3
Where in France
- Clinique Sainte ThérèseAmiens, FranceNo longer taking part
- Centre Paul PapinAngers, FranceNo longer taking part
- HospitalAngers, FranceNo longer taking part
- HospitalBrest, FranceNo longer taking part
- Centre Jean PerrinClermont-Ferrand, FranceNo longer taking part
- Centre G F LeclercDijon, FranceNo longer taking part
- HospitalLyon, FranceNo longer taking part
- Institut Paoli-CalmetteMarseille, FranceNo longer taking part
- Centre Val d'Aurelle,Montpellier, FranceNo longer taking part
- Hôpital des DiaconessesParis, FranceNo longer taking part
- Hôpital Européen Georges PompidouParis, FranceNo longer taking part
- Hôpital LariboisièreParis, FranceNo longer taking part
- Clinique MutualisteRennes, FranceNo longer taking part
- HopitalRennes, FranceNo longer taking part
- Centre René HugueninSaint-Cloud, FranceNo longer taking part
- Institut Cancerologie de l'OuestSaint-Herblain, FranceNo longer taking part
- Centre Paul StraussStrasbourg, FranceNo longer taking part
- Institut Claudius RegaudToulouse, FranceNo longer taking part
- Hopital BretonneauTours, FranceNo longer taking part
Trial details
- Who runs it
- Institut Cancerologie de l'Ouest
- Trial code
- NCT01218490
- Record updated
- 16 May 2019
- Original description
It is a multicenter randomized trial of superior cleaning compared the absence of dissection in stage III patients with optimal surgical resection without retroperitoneal lymph node palpable.Read full original descriptionShow less
Pelvic and Aortic-cava Lymphadenectomy Randomized Phase III for Advanced Ovarian Cancer
It is a multicenter randomized trial of superior cleaning compared the absence of dissection in stage III patients with optimal surgical resection without retroperitoneal lymph node palpable.
Inclusion: Age> 18 years; Karnofsky> 80, or ASA I-II; Primary ovarian adenocarcinoma, or primitive peritoneal; No retroperitoneal lymph node> 2cm (CT; MRI); Complete surgical staging; Stage III-IV FIGO classification; Indication of systemic chemotherapy before surgery or post surgery.
Exclusion: Previous pelvic lymphadenectomy or aortic-cava for a disease other than ovarian cancer; Incomplete surgery, resectable lesion, Surgery sub optimal (R> 1cm); Non Invasive Cancer; non-epithelial or borderline cancer; Pregnancy; Contraindication to Platinum and Paclitaxel; Borderline Ovarian Tumor; tumor recurrence.