Genetic study of prostate cancer in families with the disease
Studies genes and molecular factors in adults with familial prostate cancer.
Key facts
- Who runs it
- Centre de Recherche sur les Pathologies Prostatiques
- Where
- Angers, Brest, Dijon, and Paris, FranceSee the 5 sites
- Trial code
- Registry title
- Epidemiologic and Genetic Study on Familial Prostate Cancer
- Status
- Recruiting
- People taking part
- 10,000 people, planned
- Started
- Oct 1996
- Expected to end
- Dec 2026
- Type of study
- Observational
- Record updated
- 23 May 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for men with prostate cancer who come from families with hereditary prostate cancer. Healthy men without prostate cancer can also join as controls.
- Age
- 18 years or older
- Sex
- All
- Disease stage
- Prostate cancer confirmed by tissue examination (histology).
Main reasons for not taking part
- No signed informed consent
- Refusal to take part in the study
The registry criteria, word for word
Show all 5 criteriaShow less
Who can take part
- patient with a histological confirmed prostate cancer
- member of a hereditary prostate cancer family
- healthy control men without prostate cancer
Who cannot take part
- Absence of signed informed consent
- refusal to participate in the study
Where in France
- Department of Urology, CHU AngersAngers, FranceContact: Abdel-Rahmene Azzouzi, MD, PhD (principal investigator)Taking people
- Department of Urology, Hopital de la Cavale BlancheBrest, FranceContact: Georges Fournier, MD (principal investigator)Taking people
- Department of Urology, CHU DijonDijon, FranceContact: Luc Cormier, MD, PhD (principal investigator)Taking people
- Department of Urology, Hopital Pitié-SalpetriereParis, FranceContact: Marc-Olivier Bitker, MD (principal investigator)Taking people
- Department of Urology, Hopital TenonParis, FranceContact: Olivier Cussenot, MD, PhDNo longer taking part
About the trial
What the trial wants to find out
The aims of the study are:
Read full original descriptionShow less
* to identify genetic and molecular factors (rare mutations, polymorphisms) involved in the natural history of prostate cancers and their response to treatment, * to evaluate and deduce their medical applications for screening and therapeutic management of these tumors.
The group in the trial
- Men with or without Prostate Cancer
Men with a histological confirmed prostate cancer, and their family members in case of hereditary prostate cancer. Men with no prostate cancer after a screening procedure for this disease, so that their biological samples can be compared to those of men with prostate cancer.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- ProGene: Etude Genetique et Epidemiologique du Cancer de la Prostate Familial
- Plain-language title
- Genetic study of prostate cancer in families with the diseaseGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 23 May 2025