Registry study following adults with acute myeloid leukemia and related blood cancers
Collects health records and samples from adults with newly diagnosed or relapsed acute myeloid leukemia.
Plain-language title generated from the registry record
Registry title: Registry Study on Patient Characteristics, Biological Disease Profile and Clinical Outcome in Acute Myeloid Leukemia and Related Neoplasms - The Biology and Outcome (BiO)-Project
Key facts
- Where
- Aschaffenburg, Augsburg, Aurich, Bad Saarow, Berlin, Bochum, Bonn, Braunschweig, Bremen, Darmstadt, Dortmund, Düsseldorf, Essen, Esslingen am Neckar, Flensburg, Frankfurt, Freiburg im Breisgau, Fulda, Giessen, Goch, Göppingen, Göttingen, Greifswald, Halle, Hamburg, Hamm, Hanau, Hanover, Heilbronn, Herne, Homburg/Saar, Kaiserslautern, Karlsruhe, Kassel, Kiel, Krefeld, Landshut, Lebach, Lemgo, Lübeck, Lüdenscheid, Ludwigshafen, Magdeburg, Mainz, Meschede, Minden, Mühlheim, München, Mutlangen, Neuss, Offenbach, Offenburg, Oldenburg, Passau, Potsdam, Recklinghausen, Regensburg, Rostock, Saarbrücken, Saarlouis, Sande, Stuttgart, Traunstein, Trier, Tübingen, Ulm, Villingen-Schwenningen, Wernigerode, and Wuppertal, GermanySee the 86 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- How old are you?
Source: NCT01252485, who can take part
Where in Germany
- Klinikum AschaffenburgAschaffenburg, GermanyTaking people
- Klinikum AugsburgAugsburg, GermanyNo longer taking part
- Ubbo-Emmius-Klinik AurichAurich, GermanyNo longer taking part
- HELIOS Klinikum Bad SaarowBad Saarow, GermanyTaking people
- Charite Universitatsmedizin Berlin Campus Virchow KlinikumBerlin, GermanyTaking people
- Helios Klinikum Emil von BehringBerlin, GermanyTaking people
- Vivantes Klinikum am UrbanBerlin, GermanyTaking people
- Vivantes Klinikum SpandauBerlin, GermanyTaking people
- Vivantes Netzwerk für Gesundheit GmbH Klinikum NeuköllnBerlin, GermanyTaking people
- Augusta-Kranken-AnstaltBochum, GermanyTaking people
- Medizinische Universitätsklinik Knappschaftskrankenhaus BochumBochum, GermanyTaking people
- Universitätsklinikum BonnBonn, GermanyTaking people
- Stadtisches Klinikum BraunschweigBraunschweig, GermanyTaking people
- Klinikum Bremen-Mitte gGmbHBremen, GermanyTaking people
- Klinikum DarmstadtDarmstadt, GermanyTaking people
- St Johannes HospitalDortmund, GermanyTaking people
- Marien Hospital Düsseldorf GmbHDüsseldorf, GermanyTaking people
- Universitätsklinikum DüsseldorfDüsseldorf, GermanyTaking people
- Kliniken Essen-Süd Evang. Krankenhaus Essen-Werden gGmbHEssen, GermanyTaking people
- Klinikum Esslingen GmbHEsslingen am Neckar, GermanyTaking people
- St. Franziskus HospitalFlensburg, GermanyTaking people
- Städtische Kliniken Frankfurt am Main-HöchstFrankfurt, GermanyTaking people
- Medizinische UniversitätsklinikFreiburg im Breisgau, GermanyTaking people
- MVZ Osthessen Medizinisches VersorgungszentrumFulda, GermanyNo longer taking part
- Klinik der Justus-Liebig-UniversitätGiessen, GermanyTaking people
- Wilhelm-Anton-Hospital gGmbHGoch, GermanyTaking people
- Alb Fils Kliniken GmbHGöppingen, GermanyTaking people
- Universitätsmedizin GöttingenGöttingen, GermanyTaking people
- Universitätsmedizin GreifswaldGreifswald, GermanyTaking people
- Universitätsklinikum HallHalle, GermanyTaking people
- Asklepios Klinik AltonaHamburg, GermanyTaking people
- Asklepios Kliniken Hamburg GmbH St. GeorgHamburg, GermanyTaking people
- Universitätsklinikum Hamburg-EppendorfHamburg, GermanyTaking people
- Evangelisches Krankenhaus HammHamm, GermanyTaking people
- Klinikum Hanau gGmbHHanau, GermanyTaking people
- Klinikum Hannover SiloahHanover, GermanyTaking people
- Medizinische Hochschule HannoverHanover, GermanyTaking people
- SLK-Kliniken Heilbronn GmbHHeilbronn, GermanyTaking people
- Marienhospital Herne Klinikum der Ruhr-Universität BochumHerne, GermanyTaking people
- Universitätsklinikum des SaarlandesHomburg/Saar, GermanyTaking people
- Westpfalz-Klinikum - KaiserslauternKaiserslautern, GermanyTaking people
- St. Vincentius Kliniken KarlsruheKarlsruhe, GermanyTaking people
- Städtisches Klinikum KarlsruheKarlsruhe, GermanyTaking people
- Klinikum Kassel GmbHKassel, GermanyNo longer taking part
- Städtisches Krankenhaus Kiel GmbHKiel, GermanyNo longer taking part
- Helios Klinikum KrefeldKrefeld, GermanyTaking people
- Klinikum Landshut gGmbHLandshut, GermanyTaking people
- Caritas Krankenhaus LebachLebach, GermanyTaking people
- Klinikum Lippe LemgoLemgo, GermanyTaking people
- Universitätslinikum Schleswig-Holstein, LübeckLübeck, GermanyTaking people
- Klinikum LüdenscheidLüdenscheid, GermanyTaking people
- Klinikum der Stadt Ludwigshafen am Rhein gGmbHLudwigshafen, GermanyTaking people
- Klinikum Magdeburg gGmbHMagdeburg, GermanyTaking people
- Univ-Klinikum der Otto-von-Guericke-UniversitätMagdeburg, GermanyTaking people
- Universitätsklinikum der Johannes Gutenberg-Universität MainzMainz, GermanyTaking people
- Klinikum Hochsauerland GmbHMeschede, GermanyTaking people
- Johannes Wesling Klinikum MindenMinden, GermanyTaking people
- Evangelisches Krankenhaus Mülheim an der Ruhr GmbHMühlheim, GermanyTaking people
- Klinikum rechts der Isar der TU MünchenMünchen, GermanyTaking people
- Klinikum SchwabingMünchen, GermanyNo longer taking part
- Klinikum Schwäbisch-GmündMutlangen, GermanyTaking people
- Städtische Kliniken Neuss Lukaskrankenhaus GmbHNeuss, GermanyNo longer taking part
- Sana Klinikum OffenbachOffenbach, GermanyTaking people
- Ortenau Klinikum Offenburg-GengenbachOffenburg, GermanyTaking people
- Klinikum Oldenburg gGmbHOldenburg, GermanyTaking people
- Pius Hospital OldenburgOldenburg, GermanyTaking people
- Klinikum PassauPassau, GermanyTaking people
- Ernst-von-Bergmann-Klinikum Potsdam gGmbHPotsdam, GermanyTaking people
- Klinikum VestRecklinghausen, GermanyTaking people
- UniversitätsklinikumRegensburg, GermanyTaking people
- University hospital RostockRostock, GermanyTaking people
- Akademisches Lehrkrankenhaus des Saarlandes St. TheresiaSaarbrücken, GermanyTaking people
- Marienhaus Klinikum St. Elisaeth SaarlouisSaarlouis, GermanyTaking people
- Nordwest-Krankenhaus SanderbuschSande, GermanyTaking people
- Diakonie-Klinikum StuttgartStuttgart, GermanyTaking people
- Klinikum Stuttgart - KatharinenhospitalStuttgart, GermanyTaking people
- Vinzenz von Paul Kliniken gGmbH Marienhospital StuttgartStuttgart, GermanyTaking people
- Klinikum TraunsteinTraunstein, GermanyTaking people
- Klinikum Mutterhaus der Borromäerinnen gGmbHTrier, GermanyTaking people
- Krankenhaus der Barmherzigen Brüder TrierTrier, GermanyTaking people
- Medizinische Universitätsklinik TübingenTübingen, GermanyTaking people
- Universitätsklinik Ulm Labor für Zytogenetische und Molekulare DiagnostikUlm, GermanyTaking people
- University Hospital of UlmUlm, GermanyTaking people
- Schwarzwald-Baar Klinikum Villingen-Schwenningen GmbHVillingen-Schwenningen, GermanyTaking people
- Harzklinikum Dorothea Christiane ErxlebenWernigerode, GermanyTaking people
- HELIOS Klinikum WuppertalWuppertal, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Ulm
- Trial code
- NCT01252485
- Record updated
- 5 January 2026
- Original description
This is a registry study in adult patients with newly diagnosed or refractory/relapsed myeloid neoplasmsRead full original descriptionShow less
Registry Study on Patient Characteristics, Biological Disease Profile and Clinical Outcome in Acute Myeloid Leukemia and Related Neoplasms - The Biology and Outcome (BiO)-Project
This is a registry study in adult patients with newly diagnosed or refractory/relapsed myeloid neoplasms
Investigator's sites: 80-90 sites in Germany and Austria
Estimated duration of observation of an individual patient:
10 years maximum
Objectives
* To register all patients with AML and related neoplasms, newly diagnosed or relapsed/refractory in all AMLSG participating centers (completeness) * To perform rapid analyses of disease-related genetic markers (incidences, treatment recommendations) * To assess patient and family history, as well as patient characteristics * To evaluate treatment response (CR, CRh, CRi) and outcome data (event-free survival [EFS], relapse-free survival [RFS], cumulative incidence of relapse [CIR], cumulative incidence of death [CID], overall survival [OS]) * To evaluate the impact of measurable residual disease (MRD) by different methods * To assess biological disease features and correlate with clinical outcome data (prognostic and predictive markers) * To store biosamples from all patients (e.g., bone marrow, blood, plasma, normal tissue; e.g., skin biopsy, finger nails, hairs, sputum, or urine)
Inclusion: Patients with suspected diagnosis of acute myeloid leukemia and related neoplasms, newly diagnosed or relapsed/refractory, classified according to the International Consensus Classification; Age ≥ 18 years. There is no upper age limit; Signed written informed consent.
Exclusion: Severe neurological or psychiatric disorder interfering with ability to give an informed consent; No consent for registration, storage and processing of the individual patient and disease characteristics and course as well as information of the family physician about study participation; No consent for biobanking of patient's biological specimens and performance of analyses on stored material.