Follows people with early spondyloarthritis and related conditions in Germany over time

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for people with a definite diagnosis of axial spondyloarthritis, juvenile spondyloarthritis, Crohn's disease, acute anterior uveitis, or psoriatic arthritis with axial involvement.

Sex

All sexes can join.

Disease stage

A definite diagnosis of axial spondyloarthritis or juvenile spondyloarthritis, Crohn's disease, acute anterior uveitis, or psoriatic arthritis with axial involvement.

The registry criteria, word for word

What the trial wants to find out

The German Spondyloarthritis Inception cohort (GESPIC) was started 2000 as a prospective, longitudinal, multicentre, nationwide study in Germany on patients with early SpA including ankylosing spondylitis (AS, also known as radiographic axial spondyloarthritis) and non-radiographic axial SpA. The objectives of GESPIC are to learn about the course of SpA during the very early stage of the disease, to appropriately assess the outcome including radiographic progression of patients after several years of follow-up, to identify outcome predictors, to assess quality of life, function, and costs (direct and indirect costs). GESPIC has been recently expanded to recruit patients with other forms of SpA / conditions associated with SpA: acute anterior uveitis, Crohn's disease as well as with psoriasis / axial psoriatic arthritis.

The 6 groups in the trial

• Ankylosing spondylitis

  Ankylosing spondylitis according to the modified New York criteria or with the clinical diagnosis of AS/r-axSpA fulfilling the ASAS Classification Criteria AND the mNY criteria plus having the indiaction for starting a bDMARD therapy according to the treating rheumatologist

• Non-radiographic axial spondyloarthritis

  Patients with clinical characteristics of axial SpA but not fulfilling the modified New York criteria for which radiographic sacroiliitis is essential or with the clinical diagnosis of nr-axSpA fulfilling the ASAS Classification Criteria not fulfilling the mNY criteria and the indiaction for starting a bDMARD therapy according to the treating rheumatologist

• Juvenile spondyloarthritis

  Patients with juvenile spondyloarthritis (juvenile ankylosing spondylitis, juvenile non-AS-spondyloarthritis).

• Crohn's disease

  Patients with Crohn's disease

• Acute anterior uveitis

  Patients with acute anterior uveitis

• Axial psoriatic arthritis

  Patients with the clinical diagnosis of psoriatic arthritis with axial involvement (sacroiliac joints and/or spine) (axPsA)