NCT01496625Recruiting
National Eye Institute Biorepository for Retinal Diseases
NEI Intramural Biorepository for Retinal Diseases
Source: ClinicalTrials.gov · Last updated 26 Oct 2026
Brief summary (registry, in English)
Background: \- To understand diseases of the retina and the eye, information is needed about people with and without such diseases. Researchers want to study these people and follow them over time. They also want to study body tissues and blood to understand the nature of eye disease. Studying genes, cells, and tissues may help them understand why some people get eye problems and others do not, or why some people respond to treatment while others do not. Researchers want to collect physical samples and personal data to develop a National Eye Institute database. Objectives: \- To collect health information and blood and tissue samples from people with and without eye diseases, to be used in research studies. Eligibility: * Individuals at least 2 years of age with different types of eye disease. * Healthy volunteers with no history of eye disease. Design: * Participants may be recruited from National Eye Institute studies or may be referred from other sources. * Participants will be screened with a physical exam and medical history. They will also have a full eye exam. Questions will be asked about family medical history, especially about eye disease. * Blood samples will be collected. Other samples, such as saliva, tears, hair, stool, and urine, may be collected as needed. Adult participants may also provide a skin sample. * Tissue or fluid from eye collected as part of eye care or treatment may also be added to the database. * No treatment will be provided as part of this study.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 650 (estimated)
- First submitted
- 17 Dec 2011
- Start date
- 18 Jun 2012
- Lead sponsor
- National Eye Institute (NEI)
- Diseases
- Macular degeneration, Diabetic eye disease
- NCT number
- NCT01496625
What you commit to
- Study type: Observational
- Planned participants: 650
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Have a systemic disease that compromises the ability to provide adequate ophthalmologic examination or treatment.
Other
- Participants will not be eligible if they:
- Are unable or unwilling to give informed consent that includes collection and study of at least one peripheral blood sample.
- Are unable or unwilling to give informed consent that includes use of NIH medical records and clinical samples for research.
Criteria the registry did not label
- INCLUSION CRITERIA:
- Participants will be eligible if they:
- Have the ability to understand and sign an informed consent or have a parent/legal guardian to do so if they are minor children.
- Manifest diagnosed or undiagnosed retinal disease(s), or could serve as an unaffected control suitable for comparison to participants with various retinal diseases, particularly AMD and diabetic retinopathy (taking into account matching factors such as age and past ocular history).
Age in the registry: 2 years to 120 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| National Institutes of Health Clinical Center Coordinator of this site? Confirm its status | Bethesda | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.