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Testing Samples to Spot Liver Transplant Problems Early in Adults

Tests blood, urine and tissue samples to find kidney damage, rejection or hepatitis C early.

Key facts

Who runs it
Northwestern University
Where
Chicago, United StatesSee the site
Trial code
Registry title
Proteogenomic Monitoring and Assessment of Liver Transplant Recipients
Status
Recruiting
People taking part
1,000 people, planned
Started
Apr 2010
Expected to end
Dec 2031
Type of study
Observational
Record updated
22 May 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults who are having a liver transplant, from a living or deceased donor. It studies blood, urine and tissue samples.

Age
18 years or older
Sex
Women and men
Disease stage
People having a first or repeat liver transplant from a living or deceased donor.

Main reasons for not taking part

  • People who cannot or do not want to give informed consent (or whose guardian cannot or does not want to)

This trial only enrols participants who have had an organ transplant. The registry sentence this rests on: Patients undergoing primary or subsequent living or deceased donor liver transplantation.

The registry criteria, word for word

Show all 5 criteriaShow less

Who can take part

  • Male and female recipients of all races, ≥18 years of age
  • Patients undergoing primary or subsequent living or deceased donor liver transplantation
  • Subject and/or guardian must be able to provide informed consent
  • Subject and/or guardian must be able to comply with the study protocol

Who cannot take part

  • Inability or unwillingness of a participant and/or guardian to provide informed consent

Where in United States

  • Northwestern Memorial HospitalChicago, United StatesContact: Misael Villegas, BATaking people

About the trial

What the trial wants to find out

This study is being done to test blood, urine and tissue samples to see if this can help decide if CKD (Chronic Kidney Disease), AR (Acute Rejection) and HCV (Hepatitis C Virus) can be identified in its early stages. CKD damage to the kidneys, AR and HCV all lower the body's ability to function properly. Early detection of these conditions could assist with successful treatment and possibly lead to less repeat organ transplants.

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Proteogenomic Monitoring and Assessment of Liver Transplant Recipients
Plain-language title
Testing Samples to Spot Liver Transplant Problems Early in AdultsGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Record updated
22 May 2026