Myocardial Protection Effect of Simvastatin Undergoing Cardiac Surgery
Key facts
- Where
- Guangzhou, ChinaSee the site
Where in China
- The First Affiliated Hospital, Sun Yat-sen UniversityGuangzhou, ChinaContact: Cong-zhi Rao, MDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Sun Yat-sen University
- Trial code
- NCT01653223
- Record updated
- 21 April 2023
- Original description
Statins have been used to low cholesterol to prevent and treat coronary artery diseases. It was also reported that statins could protect endothelial function and cardiac function during coronary artery bypass graft. The investigators recent found simvastatin reduced myocardial injury during noncoronary artery cardiac surgery in single medical center. The investigators further investigate that whether simvastatin can protect myocardium during noncoronary artery cardiac surgery with cardiopulmonary bypass and improve cardiac function with long term use postoperatively in two medical centers.Read full original descriptionShow less
A Study of Simvastatin on Myocardial Protection and Cardiac Function Undergoing Cardiac Surgery With Cardiopulmonary Bypass
Statins have been used to low cholesterol to prevent and treat coronary artery diseases. It was also reported that statins could protect endothelial function and cardiac function during coronary artery bypass graft. The investigators recent found simvastatin reduced myocardial injury during noncoronary artery cardiac surgery in single medical center. The investigators further investigate that whether simvastatin can protect myocardium during noncoronary artery cardiac surgery with cardiopulmonary bypass and improve cardiac function with long term use postoperatively in two medical centers.
Inclusion: More than 18-year-old,; Congenital heart disease(not complex),; Isolated heart valve disease,.
Exclusion: Coronary artery disease; Allergy for statins; Poor liver function,Hepatitis; Gestation women and Breast-feeding women.