Measuring Tissue Stiffness with MRI in Several Heart and Liver Conditions
Tests an MRI method measuring stiffness of organs such as liver and heart in adults.
Key facts
- Who runs it
- Arunark Kolipaka
- Where
- Columbus, United StatesSee the site
- Trial code
- Registry title
- Magnetic Resonance Elastography as a Method to Estimate Stiffness of Soft Tissues
- Status
- Recruiting
- People taking part
- 1,000 people, planned
- Started
- Mar 2012
- Expected to end
- 1 Mar 2030
- Type of study
- Observational, 2 groups
- Record updated
- 21 October 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults who can safely have an MRI scan. It tests a scan that measures how stiff soft tissues such as the liver or heart are.
- Age
- 18 years or older
- Sex
- All sexes can join
Main reasons for not taking part
- Unapproved metal in the body
- Pregnant or possibly able to become pregnant
- Claustrophobia (fear of closed spaces)
The registry criteria, word for word
Show all 2 criteriaShow less
Who can take part
- Any participant 18 years or older and are MR safe
Who cannot take part
- That study participants will be excluded if they have any unapproved metal in their bodies, or if the volunteers are pregnant or possible of becoming pregnant. Also if the participants are claustrophobic
Where in United States
- The Ohio State University -Wexner Medical CenterColumbus, United StatesContact: Kristin L Thompson, B.S.Taking people
About the trial
What the trial wants to find out
Magnetic resonance elastography is a novel non-invasive MRI technique to obtain stiffness of soft tissues such as liver, heart, kidneys, etc. In this imaging technique a person is laid in an MR scanner and a paddle (plastic drum) is put on the area of interest to send sound vibration via a speaker placed outside the scan room which is connecting plastic drum via a plastic tube. These vibrations are scanned using MRI to estimate the stiffness of soft tissues such as liver, heart, kidneys, breast etc.
The 2 groups in the trial
- Altered Stiffness
Tissue stiffness will be evaluated in subjects those with disease conditions where stiffness changes from normal. These studies will be repeated for reproducibility.
- Healthy Volunteers
Tissue stiffness will be evaluated in normal subjects to determine the normal values. These studies will be repeated for reproducibility.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Magnetic Resonance Elastography as a Method to Estimate Stiffness of Soft Tissues
- Plain-language title
- Measuring Tissue Stiffness with MRI in Several Heart and Liver ConditionsGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 21 October 2026