Frontlight ResearchEarly access
Enrolling by invitationNo phase
Molecular Basis of Food Allergy
Key facts
- Who runs it
- Children's Hospital of Philadelphia
- Where
- Philadelphia, United StatesSee the site
- Trial code
- Status
- Enrolling by invitation
- People taking part
- 5,300 people, planned
- Started
- Jan 2011
- Expected to end
- Nov 2031
- Type of study
- Observational
- Record updated
- 21 September 2026
Who can take part
- Age
- 1 month to 65 years
- Sex
- Women and men
- Healthy volunteers
- Can take part
The registry criteria, word for word
Show all 9 criteriaShow less
Who can take part
- Males or females age 1 month to 65 years
- Diagnosis of Food Allergy. Food Allergy can be either IgE or non-IgE mediated food allergy including Eosinophilic Esophagitis and Food Protein Induced Enterocolitis
- Age and sex matched patients without food allergies
- Sibling and parents of patients with food allergies
- Age and sex matched patients without food allergies
- Sibling and parents of patients with food allergies
- Patients with atopy
Who cannot take part
- Underlying disease or medical problem that is judged to serious or risky to allow 3 ml/kg of blood to be drawn from a vein (such as serious anemia, cancer, poor vein abscess, serious infections)
- Subjects that do not meet the enrollment criteria may not be enrolled. Any violations of these criteria will be reported in accordance with Institutional Review Board (IRB) policies and procedures study procedures
Where in United States
- The Children's Hospital Of PhiladelphiaPhiladelphia, United StatesEnrolling by invitation
About the trial
What the trial wants to find out
The Study examines the molecular basis of food allergy. It explores the interaction between T cells, InKT cells, basophils and cytokines in the development of food allergy. The study also explores these factors in development of tolerance "outgrowing" food allergy. It will also explore the genetic factors that lead to the development of food allergy.
Read full original descriptionShow less
The study examines all type of food allergy including IgE mediated reactions, Eosinophilic Esophagitis and Food Protein Induced Enterocolitis
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Molecular Basis of Food Allergy and Food Tolerance
- Record updated
- 21 September 2026