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Tests blood and heart-tracing signs to detect exercise-related heart strain

Tests blood and ECG markers to detect reduced heart blood flow during exercise in adults.

Plain-language title generated from the registry record
Registry title: Biochemical and Electrocardiographic Signatures in the Detection of Exercise-induced Myocardial Ischemia

Key facts

Where
Basel, SwitzerlandSee the site

Where in Switzerland

  • University Hospital BaselBasel, SwitzerlandTaking people

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Trial details

Who runs it
University Hospital, Basel, Switzerland
Trial code
NCT01838148
Record updated
11 July 2025
Original description
The primary aim is to perform the largest study worldwide to evaluate novel biochemical and electrocardiographic signatures alone as well as in combination with the standard 12-lead exercise ECG in the detection of exercise-induced myocardial ischemia (diagnostic endpoint). The secondary aim is to evaluate these innovative tools in the risk prediction for the occurrence of cardiovascular death and acute myocardial infarction during long-term follow-up.Read full original descriptionShow less

BASEL VIII Trial - Biochemical and Electrocardiographic Signatures in the Detection of Exercise-induced Myocardial Ischemia

The primary aim is to perform the largest study worldwide to evaluate novel biochemical and electrocardiographic signatures alone as well as in combination with the standard 12-lead exercise ECG in the detection of exercise-induced myocardial ischemia (diagnostic endpoint). The secondary aim is to evaluate these innovative tools in the risk prediction for the occurrence of cardiovascular death and acute myocardial infarction during long-term follow-up.

Inclusion: Patients presenting with suspected exercise-induced myocardial ischemia referred for rest/ergometry myocardial perfusion SPECT.

Exclusion: Age < 18 years; Pregnancy; Unable or unwilling to give informed consent; Symptoms at rest or minor exertion.

ClinicalTrials.gov NCT01838148