Tests brain-signal-triggered arm stimulation for people recovering from stroke
Tests brain-signal-triggered arm muscle stimulation in adults recovering from stroke.
Plain-language title generated from the registry record
Registry title: A Closed Loop Neural Activity Triggered Stroke Rehabilitation Device
Key facts
- Where
- Madison, United StatesSee the site
Where in United States
- University of WisconsinMadison, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Wisconsin, Madison
- Trial code
- NCT02098265
- Record updated
- 17 September 2026
- Original description
The purpose of this research is to determine if two non-invasive brain stimulation techniques, muscle stimulation of the arm and neuro-stimulation through the tongue, can increase the extent of stroke recovery.Read full original descriptionShow less
A Closed Loop Neural Activity Triggered Stroke Rehabilitation Device
The purpose of this research is to determine if two non-invasive brain stimulation techniques, muscle stimulation of the arm and neuro-stimulation through the tongue, can increase the extent of stroke recovery.
Inclusion: Stroke patients with persistent upper extremity (UE) deficits; Stroke patients without UE impairments; Participants with risk factors for stroke; healthy controls; No known neurologic, psychiatric or developmental disability; Stroke patients with persistent upper extremity (UE) deficits; Moderate upper extremity (dominant right hand affected) impairment (score of 1 or 2 on the motor sub-component of the NIH stroke scale (NIHSS) and ARAT score 20-45); No upper extremity injury or conditions that limited use prior to the stroke; Pre-stroke independence with a Modified Rankin Score of 0 or 1, for the standard FES only intervention.
Exclusion: Allergic to electrode gel, surgical tape and metals; Participants under treatment for infectious diseases or having apparent oral lesions or inflammation will be excluded from the study; Allergic to electrode gel, surgical tape, and metals; Women who are pregnant or may become pregnant during the course of the study will be excluded; Participants with contraindications for MRI will be offered the opportunity to participate in the interventions study only (e.g. EEG-BCI-FES and behavioral testing); Contraindications for MRI.