Germ Cell Tumor and Testicular Tumor DNA Registry
Key facts
- Who runs it
- Memorial Sloan Kettering Cancer Center
- Where
- Basking Ridge, Cold Spring Harbor, Commack, Harrison, Middletown, Montvale, New York, and Uniondale, United StatesSee the 8 sites
- Trial code
- Status
- Recruiting
- People taking part
- 1,000 people, planned
- Started
- Jan 2014
- Expected to end
- Jan 2028
- Type of study
- Observational, 3 groups
- Treatments tested
- Questionnaires
- sample of blood or saliva
- Record updated
- 4 November 2026
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Can take part
The registry criteria, word for word
Show all 12 criteriaShow less
Who can take part
- Case Cohort
- Must be ≥ 18 years of age AND
- Must be an English-speaker AND
- Must have a diagnosis or suspicion of germ cell tumor and/or a testicular mass; Family Member Cohort
- Must be ≥ 18 years of age AND
- Must be an English-speaker AND
- Must be a blood relative of the proband. Family members of probands are eligible. These individuals need not have a diagnosis of GCT-TT, as they will be used for segregation analysis of suspected variants found in the proband; Control Cohort
- Must be ≥ 18 years of age AND
- Must be an English-speaker AND
- Must not have a personal history of cancer, with the exception of non-melanoma skin cancer, AND
- Must not have a family history of germ cell tumor or testicular tumor AND
- Must not be a blood relative of controls enrolled in this study
Where in United States
- Memorial Sloan Kettering Basking RidgeBasking Ridge, United StatesContact: Darren Feldman, MDTaking people
- Cold Springs Harbor Laboratory (Specimen Analysis)Cold Spring Harbor, United StatesContact: Richard McCombie, PhDNot yet recruiting
- Memorial Sloan Kettering CommackCommack, United StatesContact: Darren Feldman, MDTaking people
- Memorial Sloan Kettering WestchesterHarrison, United StatesContact: Darren Feldman, MDTaking people
- Memorial Sloan Kettering MonmouthMiddletown, United StatesContact: Darren Feldman, MDTaking people
- Memorial Sloan Kettering BergenMontvale, United StatesContact: Darren Feldman, MDTaking people
- Memorial Sloan-Kettering Cancer CenterNew York, United StatesContact: Darren Feldman, MDTaking people
- Memorial Sloan Kettering NassauUniondale, United StatesContact: Darren Feldman, MDNot yet recruiting
About the trial
What the trial wants to find out
This study is being done to create a registry to help us learn more about germ cell tumors (GCT) and other testicular tumors. The registry will include people with these tumors and also relatives and unrelated people without these tumors. This study will help us learn more about the prevention, diagnosis, treatment and outcome of these tumors. Studying relatives of patients and people unrelated to patients with GCT and other testicular tumors will help us understand why some people get these tumors and why some people don't.
The 3 groups in the trial
- A: suspicion of germ cell tumor and/or a testicular mass
patients with testicular GCTs and non-GCT testicular tumors, extragonadal male GCTs, and female GCTs,
Treatment: Questionnaires and sample of blood or saliva
- B: family members of Group A
relatives of patients with GCTs or testicular tumors
Treatment: Questionnaires and sample of blood or saliva
- C: healthy controls unrelated to Group A or B
healthy controls who are unrelated to Groups A or B and do not have a personal history of cancer nor a family history of GCT or non-GCT testicular tumors
Treatment: Questionnaires and sample of blood or saliva
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Record updated
- 4 November 2026