NCT02119689Active, not recruiting
Vascular Reparative Mechanism in Diabetes
Vascular Reparative Mechanism by ACE2/Ang-(1-7) in Diabetes
Source: ClinicalTrials.gov · Last updated 23 Dec 2025
Brief summary (registry, in English)
The purpose of this research study is to study blood stem cells in diabetic patients and normal patients. We would like to better understand if these cells, called endothelial precursor cells (EPCs), are not working as expected in people with diabetes. We would like to see if the function of these cells can predict the development of diabetic retinopathy. Diabetic retinopathy is an eye disease associated with diabetes in which the cells of the retina are damaged. It can cause blurred vision, vision loss, blindness or possible bleeding in the retina. Even with current treatments, the quality of life for people with diabetic retinopathy is much reduced.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 78 (estimated)
- First submitted
- 14 Apr 2014
- Start date
- 30 Oct 2011
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- University of Alabama at Birmingham
- Diseases
- Diabetic eye disease
- NCT number
- NCT02119689
What you commit to
- Study type: Observational
- Planned participants: 78
- From 30 Oct 2011 to the primary completion date, 31 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Lab values
- Current pregnancy as evidence by a urine pregnancy test as the blood from a pregnant female will influence the results of the laboratory tests
Who the study is looking for
- Men or women 18 years or older
- 39 type 1 or type 2 diabetic patients
- 13 with mild retinopathy
- 13 with moderate retinopathy
- 13 with severe, nonproliferative retinopathy
- 39 age and sex matched healthy controls
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Alabama Coordinator of this site? Confirm its status | Birmingham | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.