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Studying how body fat develops and causes obesity in children

Studies fat tissue changes in children and teens with obesity and insulin resistance.

Plain-language title generated from the registry record
Registry title: Leipzig Adipose Tissue Childhood Cohort

Key facts

Where
Leipzig, GermanySee the site

Where in Germany

  • Center for Pediatric Research Leipzig (CPL)Leipzig, GermanyTaking people

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Trial details

Who runs it
University of Leipzig
Trial code
NCT02208141
Record updated
7 November 2023
Original description
In this study the investigators hypothesize that pathological alterations in adipose tissue biology already occur during the development and progression of obesity in children and adolescents. The investigators aim to identify and characterize mechanisms and molecular targets that affect the development of adipose tissue and ensuing obesity in childhood and adolescence.Read full original descriptionShow less

Determinants of Adipose Tissue Development and Obesity in Children and Adolescents

In this study the investigators hypothesize that pathological alterations in adipose tissue biology already occur during the development and progression of obesity in children and adolescents. The investigators aim to identify and characterize mechanisms and molecular targets that affect the development of adipose tissue and ensuing obesity in childhood and adolescence.

Inclusion: body weight: 3000 g - 180 kg; suitable surgical procedure; signed informed consent by the guardians and the study participant, if older 12 years.

Exclusion: complications during surgical procedure; drug treatment; severe chronic and inflammatory diseases; acute or chronic infections; oncological diseases; clotting disorders; nil by mouth.

ClinicalTrials.gov NCT02208141