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Taking people in SwedenNo phase

Studies cerebellar mutism in children after posterior fossa brain tumour surgery

Studies why some children lose speech after surgery for a back-of-brain tumour.

Plain-language title generated from the registry record
Registry title: Cerebellar Mutism Syndrome Study

Key facts

Where
Gothenburg, Linköping, Skåne, Stockholm, Umeå, and Uppsala, SwedenSee the 6 sites

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • How old is the patient who may join a trial?
  • What type of cancer has the patient been diagnosed with?

Source: NCT02300766, who can take part

Where in Sweden

  • Sahlgrenska University HospitalGothenburg, SwedenTaking people
  • Linkoping University HospitalLinköping, SwedenTaking people
  • Skåne University HospitalSkåne, SwedenTaking people
  • Karolinska University HospitalStockholm, SwedenTaking people
  • University Hospital of UmeåUmeå, SwedenTaking people
  • Uppsala University HospitalUppsala, SwedenTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Copenhagen University Hospital, Rigshospitalet
Trial code
NCT02300766
Record updated
12 August 2026
Original description
The purpose of this study is to determine why up to 25% of the pediatric patients who have surgery for a tumor in the posterior fossa develops the Cerebellar Mutism Syndrome (CMS). Furthermore the purpose is to explore the clinical course and the best treatment of the syndrome.Read full original descriptionShow less

Nordic Study of the Cerebellar Mutism Syndrome in Children With Brain Tumours of the Posterior Fossa

The purpose of this study is to determine why up to 25% of the pediatric patients who have surgery for a tumor in the posterior fossa develops the Cerebellar Mutism Syndrome (CMS). Furthermore the purpose is to explore the clinical course and the best treatment of the syndrome.

Inclusion: Age < 18 years at the date of first imaging showing this tumour; Tumour in the cerebellum/4th ventricle/brainstem with intention to treat with surgical resection or open biopsy. Second and further surgeries are also included; Informed consent from custodial parent(s).

Exclusion: None.

ClinicalTrials.gov NCT02300766